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CALCOCO2 and LNX1
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CALCOCO2
LNX1
Gene Name
calcium binding and coiled-coil domain 2
ligand of numb-protein X 1, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Apparatus
Cytoskeleton
Membrane
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Cytoplasm
Molecular Function
Protein Binding
Protein Homodimerization Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
PDZ Domain Binding
Biological Process
Viral Process
Response To Interferon-gamma
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS
DNA methylation (variation) (
23725790
)
Protein-Protein Interactions
143 interactors:
ABLIM1
ADSL
AES
AKAP17A
AMMECR1
AP5B1
APEX2
ARHGEF39
ARHGEF5
ARNT2
BAHD1
BCL6B
BEX2
C20orf195
CBX8
CCDC185
CCDC33
CCNH
CEP57L1
CHCHD3
CPNE7
CWF19L2
DAXX
DAZAP2
DBNDD2
DCTN4
DCX
DDIT4L
DDX6
DOCK2
DUSP12
DUSP26
EEF1E1
ENKD1
EXOSC5
FAM107A
FAM161A
FAM168A
FAM189A2
FAM90A1
FARS2
FASTK
FBF1
FBXL18
FKBPL
FXR2
GABARAPL1
GABARAPL2
GATAD2B
GEMIN4
GIT2
GLYCTK
HDAC7
HOXB9
IKBKG
KANSL1
KAT7
KLHL42
LENG1
LGALS8
LIMS2
LITAF
LMF2
LMO2
LMO4
LNX1
LONRF1
LSM4
MAGOHB
MAVS
MCM10
METTL17
MID2
MOS
MTPAP
MVP
MXI1
MYO6
NAA10
NDN
NFU1
ORC5
PAPD4
PCGF1
PEF1
PEG10
PFDN5
PHF1
PIAS4
POLI
PPP1R18
PRKAB2
PRPF31
PSMA1
PSME4
PTBP1
PTBP2
RABL6
RB1CC1
RBM15
RHPN1
RIN1
RNF11
RPA2
RPL9
RPS27A
RTN4IP1
RTP5
SDCBP
SHC1
SLC15A3
SMARCD1
SMCP
SNRPB
SPATA24
SRI
STK16
TAX1BP1
TBC1D22B
TBK1
TBRG4
TCEB3B
TCL1A
TEKT3
TP53RK
TRAF2
TRAF4
TRAF6
UBAC2
UBB
UBC
VARS
VPS72
ZC2HC1C
ZNF101
ZNF205
ZNF337
ZNF408
ZNF426
ZNF451
ZNF564
ZNF581
ZNF638
218 interactors:
ABCA1
ABCB1
ABR
ACAT2
ACY3
ADRA1D
AGTRAP
AIDA
AIMP2
AKIRIN2
ALDOC
ALKBH3
AMMECR1L
APIP
APOL4
APP
ARHGAP6
ARHGEF16
ARVCF
ATPAF2
ATRIP
AURKC
BCR
BLVRA
BPIFA1
C1QTNF1
CA8
CALCOCO2
CAMK2N2
CATSPERD
CCDC101
CCDC102B
CCDC114
CCDC85B
CDA
CDC42EP4
CEP72
CGN
CIB3
CIRBP
CITED1
CLDN1
CLDN17
CLDN2
CLK2
COIL
CPNE2
CTBP1
CTNND2
CTSO
CUTC
CXADR
DAB1
DAPK1
DCTD
DCUN1D5
DDX17
DEPTOR
DNPEP
DOCK9
DPF2
DVL3
EBF4
EHMT2
EIF4H
ENOX1
EPHB3
EXOC8
FAM118A
FAM124A
FAM212B
FAM9B
FBP1
FBXL12
FHL3
GAS2L2
GDI1
GIPR
GJD4
GOLPH3L
GPR142
GRB2
GRIN1
HMBOX1
HOMEZ
HSBP1
HTR2B
HUNK
IGSF5
IL3RA
ILF3
INSC
ISCU
JOSD1
KALRN
KCNA4
KCTD1
KCTD13
KCTD17
KCTD6
KHDRBS3
KIAA1598
KLHL12
KRT15
KRTAP4-12
KRTAP4-2
KRTAP9-2
KXD1
LCLAT1
LDOC1
LGALS14
LGR6
LNX2
LRRC3B
LSM2
MAGEA11
MAGEB18
MAPK9
MEMO1
METTL21A
MRFAP1L1
MRPS24
MTMR9
MTUS2
MUSTN1
MVB12B
NADK
NAGK
NCK2
NECAB2
NEK6
NKD2
NME7
NOTCH2NL
NRCAM
NUDT14
NUMB
NUP37
NXT2
ORMDL3
OSBP2
OSGIN1
PAFAH1B3
PAICS
PBK
PBLD
PCBD1
PDZRN3
PDZRN4
PKDREJ
PKM
PKP4
POMGNT1
PPIA
PPID
PQBP1
PRR13
PTGIR
PTS
RABAC1
RAD51D
RAD54B
RBMX
RBMY1A1
RFPL3
ROBO3
ROPN1
RPIA
RUFY4
RUVBL2
SAPCD1
SAT1
SCLT1
SDK1
SLC6A15
SLC6A5
SNCB
SNRNP25
SNRPF
SPHKAP
SRSF1
SSNA1
SSTR3
STAC2
STRN
STX5
SUV39H1
SUV39H2
TBCEL
THAP7
TIFA
TMEM14C
TNFRSF18
TPM4
TRAF2
TRIM23
TRIM39
TRIM54
TRIP13
TRMT12
TSC2
TSC22D4
TSSK3
TYRO3
UBE2D2
ULK2
VCP
VRK2
WAC
WNT8A
WWP1
ZADH2
ZBTB43
ZBTB8A
ZCCHC10
ZFP64
ZNF581
ZNF593
Entrez ID
10241
84708
HPRD ID
06846
17287
Ensembl ID
ENSG00000136436
ENSG00000072201
Uniprot IDs
Q13137
Q8TBB1
PDB IDs
3VVV
3VVW
4GXL
4HAN
3B76
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Type I Interferon Production
MRNA Metabolic Process
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
JNK Cascade
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Protein Modification By Small Protein Conjugation
Activation Of MAPK Activity
Activation Of Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Signaling
Positive Regulation Of Protein Modification Process
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of Type I Interferon Production
Activation Of NF-kappaB-inducing Kinase Activity
Protein Ubiquitination
Toll-like Receptor Signaling Pathway
Positive Regulation Of MAP Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Mitotic G1 DNA Damage Checkpoint
Cellular Component Assembly
Protein Homooligomerization
Protein Oligomerization
Protein Complex Assembly
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Cellular Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Regulation Of Cellular Component Organization
Cellular Aromatic Compound Metabolic Process
Regulation Of Rho Protein Signal Transduction
Response To Stimulus
Developmental Process
Cellular Metabolic Process
Peptidyl-lysine Dimethylation
Heterocycle Metabolic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Neutrophil Degranulation
Cellular Response To Stimulus
Viral Process
Programmed Cell Death
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Splicing
Cellular Nitrogen Compound Metabolic Process
Protein Tetramerization
Cell Death
Apoptotic Process
Death
Neuron Recognition
Cell Communication
Signaling
Regulation Of Neutrophil Degranulation
Negative Regulation Of Neutrophil Activation
Viral Release From Host Cell
Regulation Of Rho GTPase Activity
Cell-cell Junction Organization
Protein Autophosphorylation
Response To Abiotic Stimulus
Organelle Organization
Regulation Of Cell Morphogenesis
Nitrogen Compound Metabolic Process
Axon Midline Choice Point Recognition
Positive Regulation Of Rho GTPase Activity
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Homodimerization Activity
Regulation Of Ras Protein Signal Transduction
Protein Heterooligomerization
Biosynthetic Process
Tagcloud
?
ad
astrocytes
atg
atgs
autophagic
autophagy
avs
beneficial
brains
clear
clearance
enhancement
expected
facilitating
flux
hippocampal
impairment
lc3
localized
microglia
mouse
ndp52
p62
phosphorylated
plaques
reflecting
sqstm1
tau
vesicles
Tagcloud (Difference)
?
ad
astrocytes
atg
atgs
autophagic
autophagy
avs
beneficial
brains
clear
clearance
enhancement
expected
facilitating
flux
hippocampal
impairment
lc3
localized
microglia
mouse
ndp52
p62
phosphorylated
plaques
reflecting
sqstm1
tau
vesicles
Tagcloud (Intersection)
?