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LSM8 and SNRPB
Number of citations of the paper that reports this interaction (PMID
22365833
)
24
Data Source:
BioGRID
(two hybrid)
LSM8
SNRPB
Gene Name
LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
small nuclear ribonucleoprotein polypeptides B and B1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Spliceosomal Complex
U4/U6 X U5 Tri-snRNP Complex
Nucleoplasm
Spliceosomal Complex
U7 SnRNP
U1 SnRNP
U4 SnRNP
U12-type Spliceosomal Complex
Cytosol
Small Nuclear Ribonucleoprotein Complex
Methylosome
SMN-Sm Protein Complex
Extracellular Vesicular Exosome
Catalytic Step 2 Spliceosome
Histone Pre-mRNA 3'end Processing Complex
Molecular Function
Protein Binding
U6 SnRNA Binding
U6 SnRNA 3'-end Binding
Poly(A) RNA Binding
Protein Binding
Poly(A) RNA Binding
Histone Pre-mRNA DCP Binding
Biological Process
MRNA Splicing, Via Spliceosome
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
Histone MRNA Metabolic Process
RNA Splicing
Gene Expression
MRNA 3'-end Processing
NcRNA Metabolic Process
Pathways
mRNA Splicing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
Metabolism of non-coding RNA
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Cleavage of Growing Transcript in the Termination Region
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
snRNP Assembly
Processing of Capped Intronless Pre-mRNA
SLBP independent Processing of Histone Pre-mRNAs
RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions
49 interactors:
ARNT
BCKDK
COL23A1
DBF4
DCP1A
DCP1B
DPAGT1
ECHDC2
EFTUD2
EXOSC10
EXOSC6
FAM63A
FERMT3
GMPPA
GTF2I
HSPA9
IFNLR1
IGHMBP2
ISOC2
ITSN2
KCTD3
LSM2
LSM3
LSM4
LSM5
LSM6
LSM7
MGA
MPRIP
MRPL48
MTHFR
NAGK
NME4
PDCD2
PGD
PHF11
RBM5
RPL24
RSC1A1
RSL24D1
SEPT10
SEPT5
SMU1
SNRNP200
SNRPB
SNRPD1
TALDO1
THUMPD3
UPF1
48 interactors:
ASCC2
BANP
C14orf1
CALCOCO2
CD2BP2
CDKN2A
CEP55
CLNS1A
COIL
CTDP1
DAB1
DDX20
DHX9
FNBP4
GEMIN4
GEMIN5
GEMIN6
GEMIN7
GIGYF2
GOLGA2
IL7R
KRT40
L3MBTL3
LSM11
LSM2
LSM8
PNMA1
PRMT5
PRMT7
PSMA3
RBPMS
RFX6
SKIV2L
SMN1
SMN2
SMNDC1
SNRPD1
SNRPD3
SNUPN
SS18L1
STRAP
STXBP2
STXBP3
TFIP11
TOP3B
TRIM23
WBP4
WDR77
Entrez ID
51691
6628
HPRD ID
06288
01655
Ensembl ID
ENSG00000125835
Uniprot IDs
A4D0W0
O95777
P14678
Q66K91
PDB IDs
1D3B
2Y9A
2Y9B
2Y9C
2Y9D
3CW1
3PGW
Enriched GO Terms of Interacting Partners
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Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Nuclear-transcribed MRNA Catabolic Process
MRNA Metabolic Process
MRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RNA Catabolic Process
Nucleobase-containing Compound Metabolic Process
Aromatic Compound Catabolic Process
RNA Splicing
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
MRNA Processing
RNA Processing
Catabolic Process
Gene Expression
RNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Cellular Macromolecule Catabolic Process
Ribonucleoprotein Complex Biogenesis
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cellular Metabolic Process
Histone MRNA Metabolic Process
Pentose Biosynthetic Process
Metabolic Process
Histone MRNA Catabolic Process
Dosage Compensation By Inactivation Of X Chromosome
Spliceosomal Complex Assembly
Dosage Compensation
Ribonucleoprotein Complex Assembly
Ribosome Biogenesis
Pentose-phosphate Shunt
Glyceraldehyde-3-phosphate Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Glucose 6-phosphate Metabolic Process
RRNA Processing
NcRNA Metabolic Process
Starch Catabolic Process
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Response To Type III Interferon
Dolichol Biosynthetic Process
NADP Metabolic Process
RRNA Metabolic Process
Spliceosomal SnRNP Assembly
Carbohydrate Biosynthetic Process
D-gluconate Metabolic Process
Response To Vitamin B2
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Splicing
MRNA Processing
RNA Processing
MRNA Metabolic Process
Ribonucleoprotein Complex Assembly
Ribonucleoprotein Complex Biogenesis
Gene Expression
RNA Metabolic Process
Cellular Macromolecular Complex Assembly
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
NcRNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Component Assembly
Spliceosomal Complex Assembly
Cellular Metabolic Process
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Neutrophil Degranulation
Chromosome Organization
Histone H4-R3 Methylation
Neutrophil Activation Involved In Immune Response
Peptidyl-arginine N-methylation
Chromatin Organization
Spliceosomal Tri-snRNP Complex Assembly
Metabolic Process
Histone Arginine Methylation
Peptidyl-arginine Methylation
Regulation Of Mitotic Cell Cycle Phase Transition
Transcription, DNA-templated
Neutrophil Mediated Immunity
Histone MRNA Metabolic Process
Chromatin Modification
Neutrophil Activation
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
Cellular Process
RNA Biosynthetic Process
Regulation Of T Cell Differentiation In Thymus
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Cell Cycle Process
Pancreatic Epsilon Cell Differentiation
Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration
SnRNA Import Into Nucleus
Spliceosomal Complex Disassembly
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