LSM8 and IFNLR1

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		LSM8	IFNLR1
Gene Name		LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)	interferon, lambda receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex	Integral Component Of Membrane Interleukin-28 Receptor Complex
	Molecular Function	Protein Binding U6 SnRNA Binding U6 SnRNA 3'-end Binding Poly(A) RNA Binding	Cytokine Receptor Activity Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Mucosal Immune Response Negative Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Response To Type III Interferon Regulation Of Defense Response To Virus By Host Defense Response To Virus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		49 interactors: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FAM63A FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MGA MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPT10 SEPT5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	3 interactors: IFNL1 IFNL2 LSM8
Entrez ID		51691	163702
HPRD ID		06288	09589
Ensembl ID			ENSG00000185436
Uniprot IDs		A4D0W0 O95777	Q8IU57
PDB IDs			3OG4 3OG6
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nucleobase-containing Compound Metabolic Process Aromatic Compound Catabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Processing RNA Processing Catabolic Process Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Metabolic Process Histone MRNA Metabolic Process Pentose Biosynthetic Process Metabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Spliceosomal Complex Assembly Dosage Compensation Ribonucleoprotein Complex Assembly Ribosome Biogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Glucose 6-phosphate Metabolic Process RRNA Processing NcRNA Metabolic Process Starch Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Response To Type III Interferon Dolichol Biosynthetic Process NADP Metabolic Process RRNA Metabolic Process Spliceosomal SnRNP Assembly Carbohydrate Biosynthetic Process D-gluconate Metabolic Process Response To Vitamin B2	JAK-STAT Cascade Negative Regulation Of Memory T Cell Differentiation Defense Response To Virus Response To Virus Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Regulation Of Memory T Cell Differentiation Positive Regulation Of Immune Response Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of Type 2 Immune Response Response To Other Organism Response To Biotic Stimulus Regulation Of Interleukin-5 Production Regulation Of Immune Response Mucosal Immune Response Positive Regulation Of Immune System Process Negative Regulation Of T Cell Differentiation Regulation Of Type 2 Immune Response Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Lymphocyte Differentiation Positive Regulation Of Interferon-gamma Production Positive Regulation Of JAK-STAT Cascade Regulation Of Immune System Process Defense Response
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