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LSM8 and DBF4
Number of citations of the paper that reports this interaction (PMID
15231747
)
44
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
LSM8
DBF4
Gene Name
LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
DBF4 zinc finger
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Spliceosomal Complex
U4/U6 X U5 Tri-snRNP Complex
Nucleoplasm
Molecular Function
Protein Binding
U6 SnRNA Binding
U6 SnRNA 3'-end Binding
Poly(A) RNA Binding
Nucleic Acid Binding
Enzyme Activator Activity
Zinc Ion Binding
Biological Process
MRNA Splicing, Via Spliceosome
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
Positive Regulation Of Catalytic Activity
Pathways
G1/S Transition
G2/M Checkpoints
Activation of ATR in response to replication stress
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
M/G1 Transition
Cell Cycle Checkpoints
Activation of the pre-replicative complex
Mitotic G1-G1/S phases
Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions
49 interactors:
ARNT
BCKDK
COL23A1
DBF4
DCP1A
DCP1B
DPAGT1
ECHDC2
EFTUD2
EXOSC10
EXOSC6
FAM63A
FERMT3
GMPPA
GTF2I
HSPA9
IFNLR1
IGHMBP2
ISOC2
ITSN2
KCTD3
LSM2
LSM3
LSM4
LSM5
LSM6
LSM7
MGA
MPRIP
MRPL48
MTHFR
NAGK
NME4
PDCD2
PGD
PHF11
RBM5
RPL24
RSC1A1
RSL24D1
SEPT10
SEPT5
SMU1
SNRNP200
SNRPB
SNRPD1
TALDO1
THUMPD3
UPF1
17 interactors:
BRCA1
CDC7
CDK2
CHAF1A
CHEK2
LSM8
MCM2
MCM3
MCM4
MCM6
MCM7
MEN1
ORC1
ORC2
ORC3
ORC5
ORC6
Entrez ID
51691
10926
HPRD ID
06288
10371
Ensembl ID
ENSG00000006634
Uniprot IDs
A4D0W0
O95777
B7Z8C6
Q9UBU7
PDB IDs
4F99
4F9A
4F9B
4F9C
Enriched GO Terms of Interacting Partners
?
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Nuclear-transcribed MRNA Catabolic Process
MRNA Metabolic Process
MRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RNA Catabolic Process
Nucleobase-containing Compound Metabolic Process
Aromatic Compound Catabolic Process
RNA Splicing
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
MRNA Processing
RNA Processing
Catabolic Process
Gene Expression
RNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Cellular Macromolecule Catabolic Process
Ribonucleoprotein Complex Biogenesis
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cellular Metabolic Process
Histone MRNA Metabolic Process
Pentose Biosynthetic Process
Metabolic Process
Histone MRNA Catabolic Process
Dosage Compensation By Inactivation Of X Chromosome
Spliceosomal Complex Assembly
Dosage Compensation
Ribonucleoprotein Complex Assembly
Ribosome Biogenesis
Pentose-phosphate Shunt
Glyceraldehyde-3-phosphate Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Glucose 6-phosphate Metabolic Process
RRNA Processing
NcRNA Metabolic Process
Starch Catabolic Process
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Response To Type III Interferon
Dolichol Biosynthetic Process
NADP Metabolic Process
RRNA Metabolic Process
Spliceosomal SnRNP Assembly
Carbohydrate Biosynthetic Process
D-gluconate Metabolic Process
Response To Vitamin B2
DNA Replication
DNA Replication Initiation
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
DNA Metabolic Process
DNA-dependent DNA Replication
Cell Cycle
Cell Cycle Process
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Macromolecule Biosynthetic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Nitrogen Compound Metabolic Process
DNA Unwinding Involved In DNA Replication
Biosynthetic Process
DNA Duplex Unwinding
DNA Geometric Change
DNA Conformation Change
Cellular Response To DNA Damage Stimulus
Chromosome Organization
Cellular Metabolic Process
Regulation Of DNA Replication
DNA Repair
Cellular Response To Stress
Organelle Organization
Regulation Of Nuclear Cell Cycle DNA Replication
Signal Transduction In Response To DNA Damage
Positive Regulation Of DNA-dependent DNA Replication
Metabolic Process
Response To Ionizing Radiation
Positive Regulation Of DNA Metabolic Process
Double-strand Break Repair
Cellular Response To Epidermal Growth Factor Stimulus
DNA Damage Checkpoint
Response To Epidermal Growth Factor
Negative Regulation Of Cell Cycle
Positive Regulation Of Histone Methylation
Regulation Of Cell Cycle Process
Regulation Of Cell Cycle
Positive Regulation Of Cell Cycle Process
Negative Regulation Of DNA Replication
Cell Cycle Checkpoint
Regulation Of Cell Cycle Phase Transition
Tagcloud
?
bud
cdc28
cdc4
cdc7
cln1
cln2
cln3
commited
conceivable
cyclins
dsc1
duplication
else
firstly
hartley
hfs1
jackson
mcb
p34cdc28
pole
principally
redundancy
rosamond
sbf
scb
scm4
smith
swi6
unpublished
Tagcloud (Difference)
?
bud
cdc28
cdc4
cdc7
cln1
cln2
cln3
commited
conceivable
cyclins
dsc1
duplication
else
firstly
hartley
hfs1
jackson
mcb
p34cdc28
pole
principally
redundancy
rosamond
sbf
scb
scm4
smith
swi6
unpublished
Tagcloud (Intersection)
?