LSM8 and MRPL48

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		LSM8	MRPL48
Gene Name		LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)	mitochondrial ribosomal protein L48
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex	Mitochondrial Inner Membrane Mitochondrial Ribosome
	Molecular Function	Protein Binding U6 SnRNA Binding U6 SnRNA 3'-end Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		49 interactors: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FAM63A FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MGA MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPT10 SEPT5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	4 interactors: APP EXOSC2 LSM8 OXA1L
Entrez ID		51691	51642
HPRD ID		06288	14767
Ensembl ID
Uniprot IDs		A4D0W0 O95777	B4DN34 Q96GC5
PDB IDs
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nucleobase-containing Compound Metabolic Process Aromatic Compound Catabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Processing RNA Processing Catabolic Process Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Metabolic Process Histone MRNA Metabolic Process Pentose Biosynthetic Process Metabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Spliceosomal Complex Assembly Dosage Compensation Ribonucleoprotein Complex Assembly Ribosome Biogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Glucose 6-phosphate Metabolic Process RRNA Processing NcRNA Metabolic Process Starch Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Response To Type III Interferon Dolichol Biosynthetic Process NADP Metabolic Process RRNA Metabolic Process Spliceosomal SnRNP Assembly Carbohydrate Biosynthetic Process D-gluconate Metabolic Process Response To Vitamin B2	MRNA Metabolic Process RNA Processing RNA 3'-end Processing Nuclear Polyadenylation-dependent TRNA Catabolic Process Synaptic Growth At Neuromuscular Junction Mitochondrial Proton-transporting ATP Synthase Complex Assembly Polyadenylation-dependent SnoRNA 3'-end Processing Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription U4 SnRNA 3'-end Processing Collateral Sprouting In Absence Of Injury TRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Proton-transporting ATP Synthase Complex Assembly Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Collateral Sprouting Axon Midline Choice Point Recognition SnoRNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Nuclear MRNA Surveillance RRNA 3'-end Processing Negative Regulation Of ATPase Activity RNA Surveillance Neuron Remodeling Negative Regulation Of Hydrolase Activity Intracellular MRNA Localization MRNA Processing RRNA Catabolic Process Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Respiratory Chain Complex I Biogenesis Protein Insertion Into Membrane Maturation Of 5.8S RRNA Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Growth Cellular Localization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Negative Regulation Of Oxidoreductase Activity Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Mitochondrial Respiratory Chain Complex Assembly Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity SnRNA Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
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