LSM8 and BCKDK

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LSM8	BCKDK
Gene Name		LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)	branched chain ketoacid dehydrogenase kinase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex	Mitochondrion Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex
	Molecular Function	Protein Binding U6 SnRNA Binding U6 SnRNA 3'-end Binding Poly(A) RNA Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity
	Biological Process	MRNA Splicing, Via Spliceosome	Protein Phosphorylation Cellular Amino Acid Catabolic Process Branched-chain Amino Acid Catabolic Process Phosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		49 interactors: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FAM63A FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MGA MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPT10 SEPT5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	6 interactors: APP EPS8 LSM8 NR5A2 STAT3 TRAF4
Entrez ID		51691	10295
HPRD ID		06288	12523
Ensembl ID			ENSG00000103507
Uniprot IDs		A4D0W0 O95777	A8MY43 O14874 Q96G95
PDB IDs
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nucleobase-containing Compound Metabolic Process Aromatic Compound Catabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Processing RNA Processing Catabolic Process Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Metabolic Process Histone MRNA Metabolic Process Pentose Biosynthetic Process Metabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Spliceosomal Complex Assembly Dosage Compensation Ribonucleoprotein Complex Assembly Ribosome Biogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Glucose 6-phosphate Metabolic Process RRNA Processing NcRNA Metabolic Process Starch Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Response To Type III Interferon Dolichol Biosynthetic Process NADP Metabolic Process RRNA Metabolic Process Spliceosomal SnRNP Assembly Carbohydrate Biosynthetic Process D-gluconate Metabolic Process Response To Vitamin B2	Intracellular Receptor Signaling Pathway Feeding Behavior Regulation Of Multicellular Organism Growth Behavior Adult Locomotory Behavior Synaptic Growth At Neuromuscular Junction Response To Ethanol Regulation Of Protein Binding Adult Behavior Collateral Sprouting In Absence Of Injury Actin Polymerization-dependent Cell Motility Chemical Homeostasis Collateral Sprouting Axon Midline Choice Point Recognition Locomotory Behavior Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Axon Choice Point Recognition Exit From Mitosis Steroid Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Binding Negative Regulation Of Glycolytic Process Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Regulation Of Signal Transduction Neuron Remodeling Radial Glial Cell Differentiation Behavioral Response To Ethanol Positive Regulation Of Protein Homodimerization Activity Signal Transduction Positive Regulation Of Signal Transduction Negative Regulation Of Cell Development Positive Regulation Of Transcription, DNA-templated Organ Development Homeostatic Process Regulation Of Signaling Interleukin-6-mediated Signaling Pathway Signaling Cell Communication RNA Metabolic Process Rac Protein Signal Transduction Movement Of Cell Or Subcellular Component Positive Regulation Of Macromolecule Biosynthetic Process MRNA Processing Cellular Copper Ion Homeostasis Positive Regulation Of Gene Expression Regulation Of Protein Homodimerization Activity Positive Regulation Of Metabolic Process Single-organism Behavior
Tagcloud ?			administering afforded akt3 ameliorated asd autism autisms clues cntn5 cntnap2 cyfip1 en2 fmr1 individually mecp2 neuroanatomical neuroligins neurorexins personalized pharmacologic phenotypically plausible polygenic scn1a shank2 siblings slc6a4 tailored tsc1
Tagcloud (Difference) ?			administering afforded akt3 ameliorated asd autism autisms clues cntn5 cntnap2 cyfip1 en2 fmr1 individually mecp2 neuroanatomical neuroligins neurorexins personalized pharmacologic phenotypically plausible polygenic scn1a shank2 siblings slc6a4 tailored tsc1
Tagcloud (Intersection) ?