LSM8 and NME4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LSM8	NME4
Gene Name		LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)	NME/NM23 nucleoside diphosphate kinase 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol
	Molecular Function	Protein Binding U6 SnRNA Binding U6 SnRNA 3'-end Binding Poly(A) RNA Binding	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Protein Complex Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process Nucleoside Metabolic Process Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Regulation Of Apoptotic Process Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways			Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS			Red blood cell traits ( 23446634)
Protein-Protein Interactions		49 interactors: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FAM63A FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MGA MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPT10 SEPT5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	7 interactors: LSM8 NME1 NME1-NME2 NME2 SOCS3 SUV39H2 TRIP13
Entrez ID		51691	4833
HPRD ID		06288	03489
Ensembl ID			ENSG00000103202
Uniprot IDs		A4D0W0 O95777	A2IDD0 O00746
PDB IDs			1EHW
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nucleobase-containing Compound Metabolic Process Aromatic Compound Catabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Processing RNA Processing Catabolic Process Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Metabolic Process Histone MRNA Metabolic Process Pentose Biosynthetic Process Metabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Spliceosomal Complex Assembly Dosage Compensation Ribonucleoprotein Complex Assembly Ribosome Biogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Glucose 6-phosphate Metabolic Process RRNA Processing NcRNA Metabolic Process Starch Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Response To Type III Interferon Dolichol Biosynthetic Process NADP Metabolic Process RRNA Metabolic Process Spliceosomal SnRNP Assembly Carbohydrate Biosynthetic Process D-gluconate Metabolic Process Response To Vitamin B2	GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process CTP Biosynthetic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Pyrimidine Nucleoside Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Purine Nucleoside Metabolic Process Response To Testosterone Cell Differentiation Ribonucleotide Metabolic Process Nucleoside Metabolic Process Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Cellular Response To Fatty Acid Ribose Phosphate Metabolic Process Response To Amine Negative Regulation Of Myeloid Leukocyte Differentiation Cellular Response To Drug Male Meiosis Cellular Response To Glucose Stimulus Response To Fatty Acid Hippocampus Development Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Negative Regulation Of Myeloid Cell Differentiation Nucleobase-containing Compound Metabolic Process Limbic System Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleotide Metabolic Process Regulation Of Myeloid Leukocyte Differentiation Cellular Nitrogen Compound Metabolic Process Response To CAMP Response To Glucose Nucleobase-containing Small Molecule Metabolic Process Response To Organophosphorus Positive Regulation Of Epithelial Cell Proliferation Developmental Process Nitrogen Compound Metabolic Process
Tagcloud ?			5q aml analysed array arrays blast cdna cluster comprising de differently ercc1 flt1 larger myelodysplastic novo pcna probes profiles progressive qrt raeb rcmd represents subtypes transformation unfavorable validated whose
Tagcloud (Difference) ?			5q aml analysed array arrays blast cdna cluster comprising de differently ercc1 flt1 larger myelodysplastic novo pcna probes profiles progressive qrt raeb rcmd represents subtypes transformation unfavorable validated whose
Tagcloud (Intersection) ?