GNPDA1 and EWSR1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GNPDA1	EWSR1
Description		glucosamine-6-phosphate deaminase 1	EWS RNA binding protein 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cajal Body Membrane
	Molecular Function	Glucosamine-6-phosphate Deaminase Activity Protein Binding Hydrolase Activity Isomerase Activity Identical Protein Binding	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Protein Binding Calmodulin Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Metabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process Generation Of Precursor Metabolites And Energy Single Fertilization N-acetylneuraminate Catabolic Process	Regulation Of DNA-templated Transcription
Pathways		Glycolysis
Drugs		Beta-D-Glucose 2-Deoxy-2-Amino Glucitol-6-Phosphate N-acetyl-D-glucosamine-6-phosphate
Diseases			Extraskeletal myxoid chondrosarcoma Myxoid liposarcoma Ewing's sarcoma Clear cell sarcoma of soft tissue
GWAS		Asthma ( 29273806 31959851) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Mean platelet volume ( 32888494) Squamous cell lung carcinoma ( 28604730)	Breast cancer ( 23535729) Pancreatic cancer ( 25086665) Platelet count ( 27863252) Platelet distribution width ( 32888494)
Interacting Genes		4 interacting genes: EWSR1 MAGEA11 PRTFDC1 STK11	164 interacting genes: ACTL6A AGT ANXA11 ARID1A ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BRME1 BTK C11orf16 CALM1 CCDC7 CCDC91 CD177 CDK12 CEACAM5 CEBPA CETP CFAP298 CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EPAS1 ERCC5 FAM131C FASN FLI1 FXR2 GNPDA1 GPBP1L1 H2BC15 HBP1 HDAC3 HERPUD1 HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 OGT PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B PTP4A2 RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SELENOI SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SMARCC1 SMARCC2 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383
Entrez ID		10007	2130
HPRD ID		09048	00592
Ensembl ID		ENSG00000113552	ENSG00000182944
Uniprot IDs		P46926	A0A0D9SFL3 Q01844
PDB IDs		1NE7	2CPE
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway HSP90-CDC37 Chaperone Complex Histone Deacetylase Binding Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Hypoxanthine Phosphoribosyltransferase Activity Guanine Salvage Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intracellular Protein-containing Complex ATP-dependent Protein Binding Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Receptor Ligand Inhibitor Activity Aryl Hydrocarbon Receptor Complex Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Telomerase Holoenzyme Complex Assembly LRR Domain Binding Regulation Of Organelle Transport Along Microtubule Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Magnesium Ion Binding Dendrite Extension Positive Regulation Of Vesicle Transport Along Microtubule Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Epithelial Cell Proliferation Involved In Prostate Gland Development Purine Ribonucleoside Salvage Guanine Metabolic Process GMP Catabolic Process Purine Nucleobase Biosynthetic Process Adhesion Of Symbiont To Host Cell Virion Attachment To Host Cell Positive Thymic T Cell Selection Anoikis Purine Nucleoside Monophosphate Catabolic Process Nucleoside Salvage Regulation Of Cellular Response To Growth Factor Stimulus Adhesion Of Symbiont To Host Cellular Response To UV-B Golgi Localization Positive T Cell Selection G1 To G0 Transition Protein Kinase Regulator Activity Histone Methyltransferase Binding Chaperone-mediated Protein Complex Assembly Dynein Axonemal Particle Protein Phosphatase Activator Activity Telomere Maintenance Via Telomerase Positive Regulation Of Protein Localization DNA Polymerase Binding Positive Regulation Of Protein Localization To Cell Surface Thymic T Cell Selection	Nucleoplasm Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Nucleus Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Organization RNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-templated Transcription Transcription Regulator Complex Chromatin Remodeling MRNA Metabolic Process Brahma Complex NpBAF Complex RNA Metabolic Process Regulation Of Gene Expression Nucleic Acid Binding Chromatin Single-stranded DNA Binding Protein-containing Complex Negative Regulation Of DNA-templated Transcription Cardiac Conduction System Development Chromatin Binding Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Protein Binding MRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Stress Nucleosome Disassembly TORC1 Signaling Negative Regulation Of Macromolecule Biosynthetic Process
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