GNPDA1 and MAGEA11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		GNPDA1	MAGEA11
Description		glucosamine-6-phosphate deaminase 1	MAGE family member A11
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	Glucosamine-6-phosphate Deaminase Activity Protein Binding Hydrolase Activity Isomerase Activity Identical Protein Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Metabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process Generation Of Precursor Metabolites And Energy Single Fertilization N-acetylneuraminate Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Glycolysis
Drugs		Beta-D-Glucose 2-Deoxy-2-Amino Glucitol-6-Phosphate N-acetyl-D-glucosamine-6-phosphate
Diseases
GWAS		Asthma ( 29273806 31959851) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Mean platelet volume ( 32888494) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		4 interacting genes: EWSR1 MAGEA11 PRTFDC1 STK11	115 interacting genes: ACMSD ACSM2B ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 BRD1 C18orf54 C22orf39 CASP7 CAVIN3 CCDC106 CCDC14 CCDC146 CCDC185 CCDC27 CCNA2 CDC20B CDKN2B CEP76 CLUAP1 CORO1A COX7A2L CSNK2A1 CTTNBP2 DLGAP1 DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A FAM161A FBXO46 GADD45GIP1 GCSH GNPDA1 HOXB5 IFI44 IL11 IL6ST ILF3 JADE3 KIAA0408 LMBR1L LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 NTAQ1 OTUB2 PCBD2 PCF11 PDE4B PHYH PIK3IP1 PIN4 PLCXD3 PNKD PNKP POLR1D PPIF PPM1K PRDX3 PRKRIP1 PSMF1 RADIL RANBP10 RBM23 REX1BD SH2D4A SNX20 SNX7 SPMIP9 STAR SUCLA2 SUOX SUV39H2 TCEA2 TCEANC TCF25 TEKTL1 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 UBE3D USP20 UTP25 VTA1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2
Entrez ID		10007	4110
HPRD ID		09048	02281
Ensembl ID		ENSG00000113552	ENSG00000185247
Uniprot IDs		P46926	G5E962 P43364
PDB IDs		1NE7	6WJH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway HSP90-CDC37 Chaperone Complex Histone Deacetylase Binding Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Hypoxanthine Phosphoribosyltransferase Activity Guanine Salvage Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intracellular Protein-containing Complex ATP-dependent Protein Binding Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Receptor Ligand Inhibitor Activity Aryl Hydrocarbon Receptor Complex Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Telomerase Holoenzyme Complex Assembly LRR Domain Binding Regulation Of Organelle Transport Along Microtubule Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Magnesium Ion Binding Dendrite Extension Positive Regulation Of Vesicle Transport Along Microtubule Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Epithelial Cell Proliferation Involved In Prostate Gland Development Purine Ribonucleoside Salvage Guanine Metabolic Process GMP Catabolic Process Purine Nucleobase Biosynthetic Process Adhesion Of Symbiont To Host Cell Virion Attachment To Host Cell Positive Thymic T Cell Selection Anoikis Purine Nucleoside Monophosphate Catabolic Process Nucleoside Salvage Regulation Of Cellular Response To Growth Factor Stimulus Adhesion Of Symbiont To Host Cellular Response To UV-B Golgi Localization Positive T Cell Selection G1 To G0 Transition Protein Kinase Regulator Activity Histone Methyltransferase Binding Chaperone-mediated Protein Complex Assembly Dynein Axonemal Particle Protein Phosphatase Activator Activity Telomere Maintenance Via Telomerase Positive Regulation Of Protein Localization DNA Polymerase Binding Positive Regulation Of Protein Localization To Cell Surface Thymic T Cell Selection	Mitochondrial Matrix Protein Binding Mitochondrion Catabolic Process
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