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NCOR1 and TAF6
Number of citations of the paper that reports this interaction (PubMedID
9611234
)
39
Data Source:
BioGRID
(pull down)
NCOR1
TAF6
Description
nuclear receptor corepressor 1
TATA-box binding protein associated factor 6
Image
GO Annotations
Cellular Component
Histone Deacetylase Complex
Chromatin
Nucleus
Nucleoplasm
Cytosol
Membrane
Transcription Repressor Complex
Mitotic Spindle
SAGA Complex
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Cytosol
Protein-containing Complex
Transcription Factor TFTC Complex
SLIK (SAGA-like) Complex
MLL1 Complex
Molecular Function
Transcription Cis-regulatory Region Binding
DNA Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Receptor Binding
Histone Deacetylase Binding
Nuclear Thyroid Hormone Receptor Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
DNA Binding
Transcription Coactivator Activity
Protein Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Aryl Hydrocarbon Receptor Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Regulation Of Ketone Metabolic Process
Locomotor Rhythm
Negative Regulation Of Glycolytic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Fatty Acid Metabolic Process
Negative Regulation Of JNK Cascade
Rhythmic Process
Spindle Assembly
Negative Regulation Of Androgen Receptor Signaling Pathway
Negative Regulation Of MiRNA Transcription
Regulation Of DNA Repair
DNA-templated Transcription Initiation
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Apoptotic Process
Negative Regulation Of Cell Population Proliferation
MRNA Transcription By RNA Polymerase II
Positive Regulation Of Apoptotic Process
Negative Regulation Of Cell Cycle
Positive Regulation Of DNA-templated Transcription
RNA Polymerase II Preinitiation Complex Assembly
Positive Regulation Of Transcription Initiation By RNA Polymerase II
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Nuclear signaling by ERBB4
Nuclear signaling by ERBB4
PPARA activates gene expression
PPARA activates gene expression
NOTCH1 Intracellular Domain Regulates Transcription
Transcriptional activation of mitochondrial biogenesis
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HDACs deacetylate histones
Notch-HLH transcription pathway
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Nuclear Receptor transcription pathway
Regulation of lipid metabolism by PPARalpha
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Loss of MECP2 binding ability to the NCoR/SMRT complex
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
HCMV Early Events
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
Cytoprotection by HMOX1
Heme signaling
Heme signaling
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Expression of BMAL (ARNTL), CLOCK, and NPAS2
Expression of BMAL (ARNTL), CLOCK, and NPAS2
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS
Adult body size (
32376654
)
C-reactive protein levels (
30388399
)
FEV1 (
30804560
)
Free thyroxine concentration (
30367059
)
Lung function (FEV1) (
26635082
)
Lung function (FVC) (
30804560
)
Lymphocyte count (
32888494
)
Brain morphology (MOSTest) (
32665545
)
Coronary artery disease (
29212778
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
98 interacting genes:
ACTN2
AR
ATXN1
ATXN1L
ATXN3
BCL6
C1D
CBFA2T2
CHD1
CHUK
CLK1
CNOT2
COPS2
CSNK2A1
CXADR
DACH1
DDX20
DHX30
DZIP3
ENO1
ESR1
ESR2
ETS1
ETS2
GABARAP
GABARAPL1
GABARAPL2
GPS2
GTF2B
H3C1
H4C1
HDAC3
HDAC5
HDAC9
HESX1
HEY2
HTT
KLF5
MAP1LC3A
MAP1LC3B
MAP1LC3C
MECP2
MYB
MYBL2
MYOD1
NCOA1
NCOA3
NCOR2
NELFE
NR1D1
NR1D2
NR1H2
NR1H3
NR2E3
NR3C1
NR6A1
OVOL2
PDCD2
PHB1
PIAS1
PML
POU1F1
PPARA
PPARD
PPARG
PTMA
PTOV1
RARA
RARG
RBPJ
RUNX1
RUNX1T1
RXRA
SAFB
SAP30
SKI
SKIL
SNW1
SP1
SPEN
SQSTM1
SUMO2
TAB2
TAF6
TAF9
TBL1X
TBL1XR1
THRA
THRB
TRIM14
TULP3
TXNRD2
VDR
ZBTB16
ZBTB33
ZBTB5
ZBTB7A
ZMYND11
26 interacting genes:
AHR
APP
BANP
BTG3
CIITA
GTF2E1
H3-4
HNF4A
NCOR1
NFYA
NFYB
NFYC
NR1D2
PIH1D2
RELA
SH3KBP1
TAF1
TAF10
TAF11
TAF12
TAF2
TAF4
TAF5
TAF7
TAF8
TAF9
Entrez ID
9611
6878
HPRD ID
02911
11807
Ensembl ID
ENSG00000141027
ENSG00000106290
Uniprot IDs
A0A994J5B8
H0Y459
O75376
Q6PGR4
A4D299
P49848
PDB IDs
2EQR
3H52
3KMZ
3N00
4MDD
4WVD
6ONI
6WMQ
6WMS
6XXS
6XYX
6XZZ
6Y17
6ZBU
8AS9
8D8I
8DKN
8DKV
8FHE
8FHG
8FKC
8FKD
8FKE
8FKF
8FKG
5FUR
6F3T
6MZC
6MZD
6MZL
6MZM
7EDX
7EG7
7EG8
7EG9
7EGA
7EGB
7EGC
7EGD
7EGE
7EGF
7EGG
7EGH
7EGI
7EGJ
7ENA
7ENC
8GXQ
8GXS
8WAK
8WAL
8WAN
8WAO
8WAP
8WAQ
8WAR
8WAS
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleoplasm
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
DNA Binding
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Nuclear Receptor Activity
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Receptor-mediated Signaling Pathway
Hormone-mediated Signaling Pathway
Regulation Of Metabolic Process
Nucleus
Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Intracellular Receptor Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
DNA-binding Transcription Factor Activity
Positive Regulation Of Metabolic Process
DNA-templated Transcription
Chromatin
Transcription By RNA Polymerase II
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Retinoic Acid Receptor Signaling Pathway
Transcription Repressor Complex
Cell Differentiation
Transcription Corepressor Activity
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Cellular Developmental Process
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Transcription Factor TFIID Complex
RNA Polymerase II General Transcription Initiation Factor Activity
DNA-templated Transcription Initiation
Transcription Initiation At RNA Polymerase II Promoter
MRNA Transcription By RNA Polymerase II
RNA Polymerase II Preinitiation Complex Assembly
MRNA Transcription
Transcription Preinitiation Complex Assembly
Positive Regulation Of Transcription Initiation By RNA Polymerase II
Positive Regulation Of DNA-templated Transcription Initiation
Regulation Of Transcription Initiation By RNA Polymerase II
Regulation Of DNA-templated Transcription Initiation
Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
DNA-templated Transcription
Transcription Factor TFTC Complex
Protein-DNA Complex Assembly
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Protein Heterodimerization Activity
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Transcription Cis-regulatory Region Binding
Nucleobase-containing Compound Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Nucleoplasm
Positive Regulation Of Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
DNA Binding
Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Macromolecule Biosynthetic Process
Nucleus
Protein-containing Complex Assembly
Positive Regulation Of Metabolic Process
MRNA Metabolic Process
Nucleic Acid Metabolic Process
Protein-containing Complex Organization
CCAAT-binding Factor Complex
Regulation Of DNA Repair
TBP-class Protein Binding
MLL1 Complex
Chromatin
Regulation Of Gene Expression
DNA-binding Transcription Factor Binding
Regulation Of Macromolecule Biosynthetic Process
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