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NCOR1 and ENO1
Number of citations of the paper that reports this interaction (PubMedID
23414517
)
48
Data Source:
BioGRID
(two hybrid)
NCOR1
ENO1
Description
nuclear receptor corepressor 1
enolase 1
Image
GO Annotations
Cellular Component
Histone Deacetylase Complex
Chromatin
Nucleus
Nucleoplasm
Cytosol
Membrane
Transcription Repressor Complex
Mitotic Spindle
Phosphopyruvate Hydratase Complex
Extracellular Space
Nucleus
Nuclear Outer Membrane
Cytoplasm
Cytosol
Plasma Membrane
Cell Cortex
Cell Surface
Membrane
M Band
Extracellular Exosome
Molecular Function
Transcription Cis-regulatory Region Binding
DNA Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Receptor Binding
Histone Deacetylase Binding
Nuclear Thyroid Hormone Receptor Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Magnesium Ion Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Transcription Corepressor Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
Transcription Corepressor Activity
RNA Binding
Phosphopyruvate Hydratase Activity
Protein Binding
Lyase Activity
Protein Homodimerization Activity
Cadherin Binding
Metal Ion Binding
GTPase Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Regulation Of Ketone Metabolic Process
Locomotor Rhythm
Negative Regulation Of Glycolytic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Fatty Acid Metabolic Process
Negative Regulation Of JNK Cascade
Rhythmic Process
Spindle Assembly
Negative Regulation Of Androgen Receptor Signaling Pathway
Negative Regulation Of MiRNA Transcription
Negative Regulation Of Transcription By RNA Polymerase II
Gluconeogenesis
Glycolytic Process
Response To Virus
Positive Regulation Of Plasminogen Activation
Negative Regulation Of Cell Growth
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Muscle Contraction
Canonical Glycolysis
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of ATP Biosynthetic Process
Pathways
Nuclear signaling by ERBB4
Nuclear signaling by ERBB4
PPARA activates gene expression
PPARA activates gene expression
NOTCH1 Intracellular Domain Regulates Transcription
Transcriptional activation of mitochondrial biogenesis
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HDACs deacetylate histones
Notch-HLH transcription pathway
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Nuclear Receptor transcription pathway
Regulation of lipid metabolism by PPARalpha
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Loss of MECP2 binding ability to the NCoR/SMRT complex
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
HCMV Early Events
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
Cytoprotection by HMOX1
Heme signaling
Heme signaling
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Expression of BMAL (ARNTL), CLOCK, and NPAS2
Expression of BMAL (ARNTL), CLOCK, and NPAS2
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
Glycolysis
Gluconeogenesis
Manipulation of host energy metabolism
Drugs
Zinc
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Adult body size (
32376654
)
C-reactive protein levels (
30388399
)
FEV1 (
30804560
)
Free thyroxine concentration (
30367059
)
Lung function (FEV1) (
26635082
)
Lung function (FVC) (
30804560
)
Lymphocyte count (
32888494
)
Asthma (
30929738
)
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) (
23453885
)
Blood protein levels (
30072576
)
Feeling tense (
29500382
)
Platelet count (
32888494
)
Plateletcrit (
27863252
32888494
)
Tonsillectomy (
27182965
28928442
)
White blood cell count (
32888494
)
White blood cell count (basophil) (
27863252
)
Interacting Genes
98 interacting genes:
ACTN2
AR
ATXN1
ATXN1L
ATXN3
BCL6
C1D
CBFA2T2
CHD1
CHUK
CLK1
CNOT2
COPS2
CSNK2A1
CXADR
DACH1
DDX20
DHX30
DZIP3
ENO1
ESR1
ESR2
ETS1
ETS2
GABARAP
GABARAPL1
GABARAPL2
GPS2
GTF2B
H3C1
H4C1
HDAC3
HDAC5
HDAC9
HESX1
HEY2
HTT
KLF5
MAP1LC3A
MAP1LC3B
MAP1LC3C
MECP2
MYB
MYBL2
MYOD1
NCOA1
NCOA3
NCOR2
NELFE
NR1D1
NR1D2
NR1H2
NR1H3
NR2E3
NR3C1
NR6A1
OVOL2
PDCD2
PHB1
PIAS1
PML
POU1F1
PPARA
PPARD
PPARG
PTMA
PTOV1
RARA
RARG
RBPJ
RUNX1
RUNX1T1
RXRA
SAFB
SAP30
SKI
SKIL
SNW1
SP1
SPEN
SQSTM1
SUMO2
TAB2
TAF6
TAF9
TBL1X
TBL1XR1
THRA
THRB
TRIM14
TULP3
TXNRD2
VDR
ZBTB16
ZBTB33
ZBTB5
ZBTB7A
ZMYND11
66 interacting genes:
AGTPBP1
ALDOA
AMBP
ARID1B
BCL6
BHLHE40
BRCA1
CBX5
CHEK2
CHKA
CLK1
COL14A1
CYSLTR2
DES
DRC2
DUX4
FANCA
FHL1
FLNC
FNDC3B
FXR1
FYN
GLIS3
GRB2
HDAC1
HEMGN
HEY2
HK2
HSP90AB1
HSPB2
ITGB1
IVNS1ABP
KDM2A
LIG4
LINC01554
LONRF3
MCPH1
MED13
MYOC
NCOR1
OGT
P4HB
PAF1
PCNA
PDE4B
PLG
PPP2R5E
RXFP3
SERPING1
SET
SGCG
SNAPC3
SRC
SUMO2
SUMO4
TCAP
TEAD1
TERT
TRAPPC2
TTN
TUBA1A
UBE3A
UPF2
YWHAQ
YWHAZ
ZBTB44
Entrez ID
9611
2023
HPRD ID
02911
01400
Ensembl ID
ENSG00000141027
ENSG00000074800
Uniprot IDs
A0A994J5B8
H0Y459
O75376
Q6PGR4
A0A024R4F1
A0A2R8Y6G6
P06733
PDB IDs
2EQR
3H52
3KMZ
3N00
4MDD
4WVD
6ONI
6WMQ
6WMS
6XXS
6XYX
6XZZ
6Y17
6ZBU
8AS9
8D8I
8DKN
8DKV
8FHE
8FHG
8FKC
8FKD
8FKE
8FKF
8FKG
2PSN
3B97
5JLZ
5LAX
5NI9
5NIG
5OCK
8TRL
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleoplasm
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
DNA Binding
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Nuclear Receptor Activity
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Receptor-mediated Signaling Pathway
Hormone-mediated Signaling Pathway
Regulation Of Metabolic Process
Nucleus
Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Intracellular Receptor Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
DNA-binding Transcription Factor Activity
Positive Regulation Of Metabolic Process
DNA-templated Transcription
Chromatin
Transcription By RNA Polymerase II
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Retinoic Acid Receptor Signaling Pathway
Transcription Repressor Complex
Cell Differentiation
Transcription Corepressor Activity
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Cellular Developmental Process
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Transmembrane Transporter Binding
Nucleus
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Intracellular Signal Transduction
Animal Organ Development
Organelle Organization
Negative Regulation Of Immune Response
Muscle Hypertrophy
Developmental Process
Negative Regulation Of Apoptotic Process
Cytoskeletal Protein Binding
Negative Regulation Of Programmed Cell Death
Z Disc
Titin-telethonin Complex
Sarcomerogenesis
Negative Regulation Of Transcription By RNA Polymerase II
Muscle Structure Development
Sarcomere Organization
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Signal Transduction
Costamere
Negative Regulation Of Macromolecule Metabolic Process
Cellular Response To Stress
Negative Regulation Of Metabolic Process
T Cell Costimulation
Identical Protein Binding
Negative Regulation Of Biosynthetic Process
Regulation Of Membrane Depolarization
Regulation Of Metabolic Process
Regulation Of Programmed Cell Death
Skeletal Muscle Myosin Thick Filament Assembly
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Response To L-glutamate
Regulation Of Gene Expression
Rhythmic Process
Sarcolemma
Negative Regulation Of Rho Protein Signal Transduction
Regulation Of DNA-templated Transcription
Actomyosin Structure Organization
Cellular Response To Platelet-derived Growth Factor Stimulus
Regulation Of RNA Biosynthetic Process
Myosin Filament Assembly
Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Tubulin Binding
Cytoskeleton Organization
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Tagcloud (Difference)
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Tagcloud (Intersection)
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