AP1M1 and TGOLN2

Number of citations of the paper that reports this interaction (PMID 7569928)
266

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, two hybrid)

		AP1M1	TGOLN2
Gene Name		adaptor-related protein complex 1, mu 1 subunit	trans-golgi network protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Extracellular Vesicular Exosome	Nucleoplasm Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Transport Vesicle
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: AP1B1 AP1M2 AP2B1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SDCCAG3 SELP SSX2IP TGOLN2 TIFA TNIP1 VAMP4 ZBTB14 ZBTB43 ZBTB44 ZBTB8A	10 interactors: AP1M1 AP1M2 AP2M1 AP3M1 AP4M1 ITGB1 KRTAP10-9 PPP1R9A PPP1R9B PRKD2
Entrez ID		8907	10618
HPRD ID		04639	04343
Ensembl ID		ENSG00000072958	ENSG00000152291
Uniprot IDs		B3KNH5 E7ENJ6 Q59EK3 Q9BXS5	O43493
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Cellular Localization Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Regulation Of Defense Response To Virus By Virus Intracellular Transport Endosomal Transport Protein Localization Lysosomal Transport Golgi Vesicle Transport Regulation Of Immune System Process Cellular Protein Localization Vacuolar Transport Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Microtubule Cytoskeleton Organization Endomembrane System Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Transport Regulation Of Cellular Process Startle Response Microtubule-based Process Endosome To Lysosome Transport Positive Regulation Of Cell Activation Cytoskeleton Organization Clathrin-mediated Endocytosis Establishment Of Protein Localization Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Membrane Organization Cellular Protein Complex Assembly Organelle Organization Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Histone H3-K9 Acetylation Intrahepatic Bile Duct Development Positive Regulation Of Natural Killer Cell Degranulation Selenium Compound Metabolic Process Cytoplasmic Transport Glutamate Receptor Signaling Pathway Convergent Extension Involved In Neural Plate Elongation Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Golgi To Lysosome Transport Neuron-neuron Synaptic Transmission	Regulation Of Defense Response To Virus By Virus Intracellular Protein Transport Cellular Protein Localization Protein Transport Regulation Of Defense Response To Virus Establishment Of Protein Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Intracellular Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Protein Localization Establishment Of Localization In Cell Viral Process Regulation Of Immune System Process Cellular Localization Antigen Processing And Presentation Of Peptide Antigen Vesicle-mediated Transport Golgi Vesicle Transport Antigen Processing And Presentation Neuron Projection Development Regulation Of Protein Localization To Plasma Membrane Membrane Organization Neuron Development Neuron Differentiation Calcium-mediated Signaling Cell Projection Organization Immune System Process Protein Kinase D Signaling Regulation Of Opioid Receptor Signaling Pathway Cellular Response To Morphine Positive Regulation Of Histone Deacetylase Activity Regulation Of Collagen Catabolic Process Dendrite Development Actin Cytoskeleton Organization Response To Growth Factor Second-messenger-mediated Signaling Actin Filament-based Process Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Response To Isoquinoline Alkaloid Calcium-independent Cell-matrix Adhesion Regulation Of Cell Growth By Extracellular Stimulus Movement Of Cell Or Subcellular Component Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Generation Of Neurons Formation Of Radial Glial Scaffolds Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Histone Deacetylase Activity Cytoplasmic Transport Positive Regulation Of Deacetylase Activity
Tagcloud ?		19p13 adaptor ap1m2 ap2m1 chromosome clathrin cloned closely distantly diverged duplication except exclusively fact genomic homolog identical insertion intron introns mapped mu1a mu1b mu2 positions proximal separation similarity syntenic
Tagcloud (Difference) ?		19p13 adaptor ap1m2 ap2m1 chromosome clathrin cloned closely distantly diverged duplication except exclusively fact genomic homolog identical insertion intron introns mapped mu1a mu1b mu2 positions proximal separation similarity syntenic
Tagcloud (Intersection) ?