AP1M1 and VAMP4

Number of citations of the paper that reports this interaction (PMID 11598115)
27

Data Source:
BioGRID (pull down, affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vitro)

		AP1M1	VAMP4
Gene Name		adaptor-related protein complex 1, mu 1 subunit	vesicle-associated membrane protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Extracellular Vesicular Exosome	Golgi Membrane Lysosome Endosome Golgi Apparatus Trans-Golgi Network Cell Surface Integral Component Of Membrane SNARE Complex
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity
	Biological Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Regulation Of Defense Response To Virus By Virus Membrane Organization	Microtubule Cytoskeleton Organization Exocytosis ER To Golgi Vesicle-mediated Transport SNARE Complex Assembly Regulation Of Golgi To Plasma Membrane Protein Transport Golgi To Plasma Membrane Protein Transport Golgi Ribbon Formation
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: AP1B1 AP1M2 AP2B1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SDCCAG3 SELP SSX2IP TGOLN2 TIFA TNIP1 VAMP4 ZBTB14 ZBTB43 ZBTB44 ZBTB8A	9 interactors: AP1M1 BCL2L13 CCDC155 CSNK2A1 PACS1 SNAP29 STX16 STX4 STX6
Entrez ID		8907	8674
HPRD ID		04639	06070
Ensembl ID		ENSG00000072958	ENSG00000117533
Uniprot IDs		B3KNH5 E7ENJ6 Q59EK3 Q9BXS5	O75379 Q6IAZ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Cellular Localization Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Regulation Of Defense Response To Virus By Virus Intracellular Transport Endosomal Transport Protein Localization Lysosomal Transport Golgi Vesicle Transport Regulation Of Immune System Process Cellular Protein Localization Vacuolar Transport Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Microtubule Cytoskeleton Organization Endomembrane System Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Transport Regulation Of Cellular Process Startle Response Microtubule-based Process Endosome To Lysosome Transport Positive Regulation Of Cell Activation Cytoskeleton Organization Clathrin-mediated Endocytosis Establishment Of Protein Localization Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Membrane Organization Cellular Protein Complex Assembly Organelle Organization Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Histone H3-K9 Acetylation Intrahepatic Bile Duct Development Positive Regulation Of Natural Killer Cell Degranulation Selenium Compound Metabolic Process Cytoplasmic Transport Glutamate Receptor Signaling Pathway Convergent Extension Involved In Neural Plate Elongation Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Golgi To Lysosome Transport Neuron-neuron Synaptic Transmission	Vesicle Fusion Vesicle Organization Organelle Fusion Golgi Vesicle Transport Membrane Fusion Membrane Organization Establishment Of Localization In Cell Golgi Ribbon Formation Protein Transport Cellular Localization Vesicle-mediated Transport Establishment Of Protein Localization Synaptic Vesicle Fusion To Presynaptic Membrane Intracellular Protein Transport Protein Localization Regulation Of Defense Response To Virus By Virus Endosomal Transport Cellular Protein Localization Intracellular Transport Intra-Golgi Vesicle-mediated Transport Synaptic Vesicle Exocytosis Establishment Of Organelle Localization Retrograde Transport, Endosome To Golgi Organelle Organization Golgi Organization Chromosome Localization To Nuclear Envelope Involved In Synapsis Organelle Localization Vesicle Docking Regulation Of Defense Response To Virus Endomembrane System Organization Post-Golgi Vesicle-mediated Transport Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Positive Regulation Of Eosinophil Degranulation Regulation Of Neurotransmitter Levels Neurotransmitter Transport Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Establishment Of Vesicle Localization Regulation Of Cysteine-type Endopeptidase Activity Vesicle Localization Positive Regulation Of Protein Localization To Cell Surface Autophagic Vacuole Fusion Pigment Granule Maturation Endosome To Melanosome Transport Positive Regulation Of Immunoglobulin Secretion Synaptic Vesicle Priming Transport Cellular Pigment Accumulation SNARE Complex Assembly
Tagcloud ?		19p13 adaptor ap1m2 ap2m1 chromosome clathrin cloned closely distantly diverged duplication except exclusively fact genomic homolog identical insertion intron introns mapped mu1a mu1b mu2 positions proximal separation similarity syntenic	adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 verify vps4b wizened
Tagcloud (Difference) ?		19p13 adaptor ap1m2 ap2m1 chromosome clathrin cloned closely distantly diverged duplication except exclusively fact genomic homolog identical insertion intron introns mapped mu1a mu1b mu2 positions proximal separation similarity syntenic	adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 verify vps4b wizened
Tagcloud (Intersection) ?