AP1M1 and ENTR1

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		AP1M1	ENTR1
Description		adaptor related protein complex 1 subunit mu 1	endosome associated trafficking regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Early Endosome Golgi Apparatus Cytosol Plasma Membrane Membrane AP-1 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Specific Granule Membrane Synapse Extracellular Exosome	Cytoplasm Endosome Early Endosome Centrosome Cytoskeleton Midbody Retromer Complex Ciliary Basal Body Cell Projection Recycling Endosome
	Molecular Function	Protein Binding Clathrin Adaptor Activity	Protein Binding
	Biological Process	Intracellular Protein Transport Protein Transport Vesicle-mediated Transport Melanosome Organization Endosome To Melanosome Transport Platelet Dense Granule Organization Melanosome Assembly	Protein Transport Cell Projection Organization Endocytic Recycling Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Cell Division Positive Regulation Of Protein Localization To Cilium
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668)
Interacting Genes		103 interacting genes: AMOT AP1M2 AP2B1 ARFRP1 ARL6IP4 ARNT2 ATF4 AXIN2 BACH2 BCAR3 BRCA1 C7orf57 CASP8 CCDC33 CEP57L1 CORO7 CTLA4 DCX DISC1 DVL2 DZIP3 EFEMP2 EHD2 ENTR1 ETV6 EVI5L FAM219B FAM9B FKBP7 FXR1 FXR2 GAK GCSAM GRIN2A GRIN2B HNRNPC HOOK1 HOOK2 IKZF1 KIF13A KIF24 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 LAMP1 LDOC1 LNX1 LRATD2 LRMDA LZTS1 LZTS2 MDK MEA1 MID2 MTF1 MYOD1 NECAB1 NKAP NKAPD1 OLIG3 PAX6 PHC2 PICK1 PIGR PNMA5 PURB RAPGEF3 ROPN1 RP9 RSPH14 RUNDC3A SDCBP2 SELP SLC2A4 SP4 SPATA6 SRPK2 SSX2IP TEPSIN TFIP11 TGOLN2 THAP6 TIFA TNIP1 TRIM27 TRIM41 UBC VAMP4 VANGL2 ZBTB14 ZBTB3 ZBTB43 ZBTB44 ZBTB8A ZCCHC17 ZNF19 ZNF219 ZNF276 ZNF552 ZNF655 ZNF8 ZSCAN16	12 interacting genes: AP1M1 APP AXIN1 CD99 CHD3 CSNK1E DDX6 GIT1 NOD2 SDCBP SMURF1 VIM
Entrez ID		8907	10807
HPRD ID		04639	15307
Ensembl ID		ENSG00000072958	ENSG00000165689
Uniprot IDs		B3KNH5 Q59EK3 Q9BXS5	Q96C92
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding Post-Golgi Vesicle-mediated Transport Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Domain Specific Binding Convergent Extension Involved In Neural Plate Elongation Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Trans-Golgi Network Membrane Regulation Of Transcription By RNA Polymerase II Clathrin-coated Endocytic Vesicle Cellular Localization Intracellular Transport Developmental Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Synaptic Plasticity Negative Regulation Of RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Protein Complex Involved In Cell Adhesion Microtubule Convergent Extension Involved In Organogenesis Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion FHF Complex Regulation Of Neuronal Synaptic Plasticity Negative Regulation Of Regulatory T Cell Differentiation Convergent Extension Involved In Gastrulation Dentate Gyrus Development Protein Localization To Membrane Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity NMDA Glutamate Receptor Activity Regulation Of RNA Biosynthetic Process	Positive Regulation Of Catabolic Process Positive Regulation Of JNK Cascade Regulation Of JNK Cascade Positive Regulation Of Proteolysis Cellular Response To Muramyl Dipeptide Regulation Of Interleukin-1 Beta Production Positive Regulation Of Metabolic Process Regulation Of Interleukin-1 Production Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process I-SMAD Binding Regulation Of Primary Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Proteolysis Growth Cone Protein Serine/threonine Kinase Binding Positive Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Focal Adhesion Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Muramyl Dipeptide R-SMAD Binding Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Negative Regulation Of Signal Transduction Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Lipopolysaccharide Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Cellular Localization Frizzled Binding Negative Regulation Of Cell Communication Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cell Differentiation Cytosol Cellular Response To Molecule Of Bacterial Origin Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Catabolic Process Cytoplasm Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor Protein Domain Specific Binding Amyloid-beta Complex Regulation Of Canonical Wnt Signaling Pathway Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Plasma Membrane Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding
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