RAD51 and BCCIP

Number of citations of the paper that reports this interaction (PMID 15713648)
27

Data Source:
HPRD (in vivo)

		RAD51	BCCIP
Gene Name		RAD51 recombinase	BRCA2 and CDKN1A interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Condensed Chromosome Condensed Nuclear Chromosome Lateral Element Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Microtubule Organizing Center PML Body Perinuclear Region Of Cytoplasm	Nucleus Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex
	Molecular Function	Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding Protein C-terminus Binding Identical Protein Binding Single-stranded DNA-dependent ATPase Activity DNA Polymerase Binding	Protein Binding Kinase Regulator Activity Poly(A) RNA Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Recombinase Assembly DNA Unwinding Involved In DNA Replication DNA Repair Double-strand Break Repair DNA Recombination Mitotic Recombination Cellular Response To DNA Damage Stimulus Meiotic Nuclear Division Reciprocal Meiotic Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA Ligation Protein Homooligomerization Cellular Response To Ionizing Radiation Cellular Response To Camptothecin	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Repair Cell Cycle Neuroendocrine Cell Differentiation
Pathways		Assembly of the RAD51-ssDNA nucleoprotein complex Homologous DNA pairing and strand exchange Meiotic recombination Homologous Recombination Repair Homologous recombination repair of replication-independent double-strand breaks Double-Strand Break Repair Presynaptic phase of homologous DNA pairing and strand exchange
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: ABL1 ATM ATRX BCCIP BLM BRCA1 BRCA2 CASP3 CASP7 CHD3 CHEK1 DMC1 DNAJA3 ERCC2 FANCD2 FBXO18 HID1 HNRNPC IRS1 MDC1 NXF1 PFN1 RAD18 RAD51AP1 RAD51AP2 RAD51C RAD52 RAD54B RAD54L RPA1 RPA3 SFR1 SUMO1 SWI5 SWSAP1 TP53 UBE2I UGDH UHRF2 VIM WRN ZDHHC17	13 interactors: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDKN1A CSNK2B FAM46A HIST1H2BN ITSN2 PTN RAD51 RPL23
Entrez ID		5888	56647
HPRD ID		01557	16542
Ensembl ID		ENSG00000051180	ENSG00000107949
Uniprot IDs		Q06609	B4DUS0 B4E318 Q9P287
PDB IDs		1B22 1N0W
Enriched GO Terms of Interacting Partners?		DNA Metabolic Process DNA Repair Cellular Response To DNA Damage Stimulus Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination Cellular Response To Stress Response To Stress Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Radiation Cellular Nitrogen Compound Metabolic Process Chromosome Organization Response To Ionizing Radiation Organelle Organization Cell Cycle Nitrogen Compound Metabolic Process Cellular Response To Stimulus DNA Duplex Unwinding DNA Geometric Change Response To Abiotic Stimulus Regulation Of Cell Cycle Response To Stimulus Cell Cycle Process DNA-dependent DNA Replication DNA Replication Signal Transduction In Response To DNA Damage Meiotic Nuclear Division Cellular Response To Ionizing Radiation DNA Conformation Change Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Cell Aging Response To UV Meiotic Cell Cycle Cellular Response To Radiation DNA Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Process Cellular Metabolic Process Replication Fork Processing Cellular Response To Hydroxyurea Intrinsic Apoptotic Signaling Pathway Meiosis I Response To Gamma Radiation Signal Transduction By P53 Class Mediator DNA Recombinase Assembly Regulation Of Response To DNA Damage Stimulus	Cell Cycle Response To Ionizing Radiation Cell Cycle Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To Ionizing Radiation Cellular Response To DNA Damage Stimulus Cell Aging Double-strand Break Repair Via Homologous Recombination DNA Damage Response, Signal Transduction By P53 Class Mediator Recombinational Repair Signal Transduction In Response To DNA Damage Negative Regulation Of MRNA 3'-end Processing Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Radiation Meiosis I DNA-dependent DNA Replication Signal Transduction By P53 Class Mediator Positive Regulation Of DNA Ligation Cellular Response To Camptothecin G2/M Transition Of Mitotic Cell Cycle Response To Camptothecin Response To UV Cellular Response To Radiation Cell Cycle Arrest DNA Recombinase Assembly Intestinal Epithelial Cell Maturation Double-strand Break Repair Cell Maturation DNA Repair Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Filopodium Assembly Xenobiotic Transport Protein-DNA Complex Assembly Meiotic Nuclear Division Negative Regulation Of Protein Export From Nucleus Cellular Macromolecular Complex Assembly Positive Regulation Of Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Protein K6-linked Ubiquitination Cellular Response To UV-B Replication Fork Protection Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Proliferation Adiponectin-activated Signaling Pathway Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Ribosomal Protein Import Into Nucleus Regulation Of Cell Proliferation Meiotic Cell Cycle
Tagcloud ?		boundary box cerevisiae consisting damaging declined delta dosage dsc1 elements enhances fluctuate fluctuation frequency mbf1 mbp1 mcb meiosis meiotic mitotic mlu rad54 recombination saccharomyces spore sporulation swi6 transcript viability	abundantly albeit antagonizes fbp fbp1 fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated
Tagcloud (Difference) ?		boundary box cerevisiae consisting damaging declined delta dosage dsc1 elements enhances fluctuate fluctuation frequency mbf1 mbp1 mcb meiosis meiotic mitotic mlu rad54 recombination saccharomyces spore sporulation swi6 transcript viability	abundantly albeit antagonizes fbp fbp1 fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated
Tagcloud (Intersection) ?