NGFRAP1 and CTNNBL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NGFRAP1	CTNNBL1
Gene Name		nerve growth factor receptor (TNFRSF16) associated protein 1	catenin, beta like 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane
	Molecular Function	Death Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Metal Ion Binding	Protein Binding Enzyme Binding
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Multicellular Organismal Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Apoptotic Signaling Pathway	MRNA Splicing, Via Spliceosome Apoptotic Process RNA Splicing Gene Expression Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process
Pathways		Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE p75 NTR receptor-mediated signalling NADE modulates death signalling	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Bone mineral density ( 17903296)
Protein-Protein Interactions		28 interactors: AIMP2 CACYBP CCDC116 CCDC85B CTNNBL1 DIABLO EMILIN1 FSD2 GOLGA8EP GOLGA8F MIF MNAT1 NECAB2 NGFR NTRK3 PTPN13 SIVA1 SMPD1 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TSC1 USHBP1 VTA1 YWHAE	24 interactors: BUD31 CALCOCO1 CATIP CDC5L CDCA7L CREBZF CWC15 HNRNPK IK LDOC1 LUC7L MED4 MEOX2 NGFRAP1 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP U2SURP WBP11 ZCCHC10
Entrez ID		27018	56259
HPRD ID		02291	10850
Ensembl ID		ENSG00000166681	ENSG00000132792
Uniprot IDs		Q00994	B4DE16 Q8WYA6
PDB IDs		1SA6	4HM9 4HNM
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Protein Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Positive Regulation Of Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Metabolic Process Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Catalytic Activity Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process NIK/NF-kappaB Signaling Positive Regulation Of Cellular Protein Metabolic Process Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Cellular Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Apoptotic Signaling Pathway Positive Regulation Of Cytokine Production Involved In Immune Response Cellular Response To Stimulus Regulation Of MAPK Cascade Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Cell Death TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Signaling Pathway Response To Organic Substance MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Regulation Of RNA Metabolic Process Cellular Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Nuclear Speck Organization Spliceosomal Complex Assembly Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecular Complex Assembly Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Transcription, DNA-templated Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Splicing Macromolecule Biosynthetic Process Somite Specification Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Transcription From RNA Polymerase II Promoter Cellular Process Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Metabolic Process
Tagcloud ?		abcf2 adprtl1 amy2b arhgap4 atp6ap1 axin1 casp4 cox1 cox7b ctsl etv4 lgals3bp mgc35136 mgc5528 mt2a mt3 p53scv ppia prdx2 psap scgb2a2 smoc2 sptan1 sra1 tax1bp1 tpd52l1 tra1 trf4 tuba4
Tagcloud (Difference) ?		abcf2 adprtl1 amy2b arhgap4 atp6ap1 axin1 casp4 cox1 cox7b ctsl etv4 lgals3bp mgc35136 mgc5528 mt2a mt3 p53scv ppia prdx2 psap scgb2a2 smoc2 sptan1 sra1 tax1bp1 tpd52l1 tra1 trf4 tuba4
Tagcloud (Intersection) ?