CREB5 and ADAMTSL4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CREB5	ADAMTSL4
Gene Name		cAMP responsive element binding protein 5	ADAMTS-like 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protease Binding Metalloendopeptidase Activity Protein Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Adipose Tissue Development	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Attention deficit hyperactivity disorder ( 18839057) Crohn's disease ( 23128233) Diabetic retinopathy ( 21441570)	Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		37 interactors: ADAMTSL4 ATF2 COL8A1 EFEMP2 FOS FOSL1 FOSL2 JUN KIFC3 KRT15 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 KRTAP9-4 MDFI MGAT5B MTUS2 NOTCH2NL RBPMS RGS20 RIMBP3 SPRY1 SPRY2 TRAF2 TRIM23 TRIP6 TSGA10	106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587
Entrez ID		9586	54507
HPRD ID		09896	18237
Ensembl ID		ENSG00000146592	ENSG00000143382
Uniprot IDs		Q02930	F8WAD0 Q6UY14 Q9UFG7
PDB IDs
Enriched GO Terms of Interacting Partners?		TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Response To Corticosterone Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Response To CAMP Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Response To Mineralocorticoid Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organophosphorus Response To Progesterone Regulation Of Neurotrophin TRK Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Purine-containing Compound Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Response To Reactive Oxygen Species MyD88-dependent Toll-like Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Response To Mechanical Stimulus MAPK Cascade Regulation Of Innate Immune Response Response To Gravity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Organ Morphogenesis Branch Elongation Of An Epithelium Regulation Of Protein Phosphorylation Learning Cellular Response To Inorganic Substance Response To Glucocorticoid Negative Regulation Of GTPase Activity Response To Corticosteroid Axis Elongation Response To Oxidative Stress Regulation Of Protein Import Into Nucleus Tissue Development Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway	Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		additionally biomarkers carcinoid col4a3 differentially expressions favorable fc fcs meaningful member mirnas mrnas mutated neoplasms neuroendocrine overlapped pcts predicted prediction profiling ptprb repeated tools top tp53 uncovered warrant yielded	abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Difference) ?		additionally biomarkers carcinoid col4a3 differentially expressions favorable fc fcs meaningful member mirnas mrnas mutated neoplasms neuroendocrine overlapped pcts predicted prediction profiling ptprb repeated tools top tp53 uncovered warrant yielded	abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Intersection) ?