HCK and LCP2

  • Number of citations of the paper that reports this interaction (PMID 12029088)
  • 18
  • Data Source:
  • HPRD (in vitro)

HCK

LCP2

Gene Name HCK proto-oncogene, Src family tyrosine kinase lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 69 interactors: ABL1 ABL2 ACTB ADAM15 AGK APP ARRB1 ASAP1 BCAR1 BCR BTK C2orf44 CBL CCR3 CD2AP CHST15 CREBBP CSF2RB CSF3R CSK DNM2 DOK1 DOK2 ELMO1 ERBB3 EVL FASLG FCGR1A FCGR2A GOPC HNRNPK IL6ST INPP5D IRF2BPL KHDRBS1 KIT KRT40 KRTAP10-9 LCP2 MAP4K5 MTUS2 NOTCH2NL PAK2 PECAM1 PIK3CB PIK3R1 PIK3R2 PLAUR PLCG1 PLCG2 RAPGEF1 RASA1 RASA3 RPL10 SF3B3 SH3BP1 SH3KBP1 SKAP2 SOS1 SPRR2A STAT3 TNK2 TRPV4 TSG101 UNC119 VAV1 WAS WIPF1 WNT2 39 interactors: APP BLNK CBL CD22 CLNK FXR2 FYB FYN GOLGA2 GRAP2 GRB2 HCK ITK LAT LCK LYN MAP4K1 NCK1 NCK2 PAG1 PIK3R1 PLCG1 PLCG2 PRAM1 PTPN6 PTPRC SH3GL2 SHB SHC1 STAM2 SYK TRAT1 TXK VAV1 VAV3 WAS YBX1 YWHAZ ZAP70
Entrez ID 3055 3937
HPRD ID 00796 03362
Ensembl ID ENSG00000101336
Uniprot IDs A8K4G3 P08631 Q13094
PDB IDs 1AD5 1BU1 1QCF 2C0I 2C0O 2C0T 2HCK 2HK5 2OI3 2OJ2 3HCK 3NHN 3RBB 3REA 3REB 3VRY 3VRZ 3VS0 3VS1 3VS2 3VS3 3VS4 3VS5 3VS6 3VS7 4HCK 5HCK 1H3H 1YWO 2EAP 2ROR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
32dcl3  32p  antisera  cbl  eliminated  engagement  fusion  fyn  gst  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
aurkb  bub1b  ccnb1  cd247  cd3d  cd3g  cd8a  cdc20  cdca8  cenpa  cytoscape  dihydroxyfluorane  epstain  generank  hindering  itgb5  itk  kif2c  limma  lymphoblasts  mad2l1  nup37  pik3r3  plcg2  prkcq  rpa3  softwares  vav3  zap70 
Tagcloud (Difference) ?
32dcl3  32p  antisera  cbl  eliminated  engagement  fusion  fyn  gst  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
aurkb  bub1b  ccnb1  cd247  cd3d  cd3g  cd8a  cdc20  cdca8  cenpa  cytoscape  dihydroxyfluorane  epstain  generank  hindering  itgb5  itk  kif2c  limma  lymphoblasts  mad2l1  nup37  pik3r3  plcg2  prkcq  rpa3  softwares  vav3  zap70 
Tagcloud (Intersection) ?