MAP4K4 and NCK1

  • Number of citations of the paper that reports this interaction (PMID 9135144)
  • 46
  • Data Source:
  • HPRD (in vivo, in vitro)

MAP4K4

NCK1

Gene Name mitogen-activated protein kinase kinase kinase kinase 4 NCK adaptor protein 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-Protein Interactions 18 interactors: BRCA1 CASP8 DOK1 GBP3 HIST2H2BE ITGB1 KIF26B KIF5A MAP3K7 NCK1 NME7 PPP1CA PPP1CC PRKCE RAP2A RASA1 SLC9A1 TBPL2 76 interactors: ABI1 ABL1 ADAM15 ARHGAP32 ARHGEF7 BCAR1 BLNK BRK1 CAV2 CBL CBLB CD3E CRK CSNK1G2 CYFIP2 DAG1 DCC DNM1 DOK1 DOK2 DRD3 DRD4 EGFR EIF2B2 EIF2S2 EPHB1 EPHB2 ERBB3 FASLG FGFR1 FLT1 FLT3 FRS2 GAB2 KDR KHDRBS1 KIAA1522 LCP2 LPHN2 MAP4K1 MAP4K4 MINK1 NCKAP1 NCKAP5 NCKIPSD NEDD9 NPHS1 NTRK2 PAK1 PAK2 PAK3 PDGFRB PFN1 PHC2 PKN2 PLCG1 PTK2 PXN RAC1 RASA1 RHOU RRAS SHANK3 SOCS1 SOCS7 SOS1 SYNJ2 SYNPO TBK1 TNIK TNK2 UBA52 WAS WASF1 WASL WIPF1
Entrez ID 9448 4690
HPRD ID 05235 02740
Ensembl ID ENSG00000071054 ENSG00000158092
Uniprot IDs B7Z3V5 O95819 P16333
PDB IDs 2CI8 2CI9 2CUB 2JS0 2JS2 2JW4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abstract  array  cascade  complicated  crc  downregulated  downstream  dual  evidences  explored  jun  kaplan  luciferase  mdm2  meier  microarray  micrornas  mir  mirna  mirnas  multistep  noncancerous  numerous  obstacles  obviously  reporter  serve  tnm  tumorigenesis 
adaptor  biogenesis  biosynthesis  compatible  delays  dephosphorylated  dephosphorylation  faster  homology  insulinoma  islets  juxtamembrane  littermates  min6  negatively  nonphosphorylatable  pancreatic  perk  proinsulin  protecting  proteostasis  py  regulates  sh2  threonine  transmembrane  y  y561f 
Tagcloud (Difference) ?
abstract  array  cascade  complicated  crc  downregulated  downstream  dual  evidences  explored  jun  kaplan  luciferase  mdm2  meier  microarray  micrornas  mir  mirna  mirnas  multistep  noncancerous  numerous  obstacles  obviously  reporter  serve  tnm  tumorigenesis 
adaptor  biogenesis  biosynthesis  compatible  delays  dephosphorylated  dephosphorylation  faster  homology  insulinoma  islets  juxtamembrane  littermates  min6  negatively  nonphosphorylatable  pancreatic  perk  proinsulin  protecting  proteostasis  py  regulates  sh2  threonine  transmembrane  y  y561f 
Tagcloud (Intersection) ?