MAP4K4 and KIF26B

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		MAP4K4	KIF26B
Gene Name		mitogen-activated protein kinase kinase kinase kinase 4	kinesin family member 26B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytoplasm Kinesin Complex Microtubule
	Molecular Function	Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding	Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Protein Phosphorylation Signal Transduction By Phosphorylation Microvillus Assembly Intracellular Signal Transduction Regulation Of JNK Cascade Regulation Of Catalytic Activity	Microtubule-based Movement Metabolic Process Positive Regulation Of Cell-cell Adhesion Establishment Of Cell Polarity Ureteric Bud Invasion
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)	Schizophrenia ( 23212062)
Protein-Protein Interactions		18 interactors: BRCA1 CASP8 DOK1 GBP3 HIST2H2BE ITGB1 KIF26B KIF5A MAP3K7 NCK1 NME7 PPP1CA PPP1CC PRKCE RAP2A RASA1 SLC9A1 TBPL2	6 interactors: CDK1 CDK2 CDK5 CDK6 MAP4K4 TRAF2
Entrez ID		9448	55083
HPRD ID		05235	13332
Ensembl ID		ENSG00000071054	ENSG00000162849
Uniprot IDs		B7Z3V5 O95819	Q2KJY2
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To External Stimulus Regulation Of Cell Adhesion Multicellular Organismal Development Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Negative Regulation Of Signaling Developmental Process Signaling Regulation Of Signaling Enzyme Linked Receptor Protein Signaling Pathway Cell Communication Response To Stimulus Cellular Response To Organic Substance Anatomical Structure Development Regulation Of Cellular Component Organization Negative Regulation Of Cell Death Regulation Of Apoptotic Process System Development Positive Regulation Of Cell Adhesion Regulation Of Cell Death Signal Transduction Response To Abiotic Stimulus Response To Other Organism Response To Transforming Growth Factor Beta Regulation Of Cell-substrate Adhesion Cell Projection Organization Response To Biotic Stimulus Nervous System Development Cellular Response To Mechanical Stimulus MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway Regulation Of Cytoskeleton Organization Intracellular Signal Transduction Toll-like Receptor 4 Signaling Pathway Defense Response Response To Organic Substance Axonogenesis Regulation Of Organelle Organization Negative Regulation Of Necroptotic Process Negative Regulation Of Programmed Cell Death Axon Development Negative Regulation Of Necrotic Cell Death Response To Stress Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Necroptotic Process Movement Of Cell Or Subcellular Component	Cellular Response To Reactive Oxygen Species Cell Division Negative Regulation Of Cell Cycle Cellular Response To Nitric Oxide Protein Phosphorylation Response To Nitric Oxide G1/S Transition Of Mitotic Cell Cycle Cellular Protein Modification Process Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Response To Reactive Oxygen Species Cellular Response To Reactive Nitrogen Species Cellular Response To Oxidative Stress Regulation Of Protein Ubiquitination Phosphorylation Regulation Of Protein Localization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cell Cycle Cellular Protein Metabolic Process Histone Phosphorylation Regulation Of Cellular Localization Regulation Of Catalytic Activity Peptidyl-threonine Phosphorylation Centrosome Cycle TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Response To Oxidative Stress Positive Regulation Of DNA Replication Positive Regulation Of Protein Binding MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Phosphorylation Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Hippocampus Development Phosphate-containing Compound Metabolic Process Positive Regulation Of Protein Kinase Activity Cell Cycle Response To Inorganic Substance Positive Regulation Of Kinase Activity Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway Signaling Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Phosphorus Metabolic Process Cell Communication Mitotic DNA Damage Checkpoint Positive Regulation Of Transferase Activity Cell Dedifferentiation Pronuclear Fusion
Tagcloud ?		abstract array cascade complicated crc downregulated downstream dual evidences explored jun kaplan luciferase mdm2 meier microarray micrornas mir mirna mirnas multistep noncancerous numerous obstacles obviously reporter serve tnm tumorigenesis	adenomatous arhgap causative cntn6 cnv cnvs ctnnb1 etiologically filtered focad german germline hsph1 kiaa1797 mcm3ap mining mutyh ngs nonrecurrent polyposis predispose predisposition prioritized silico stringent truncating uncover unexplained ybey
Tagcloud (Difference) ?		abstract array cascade complicated crc downregulated downstream dual evidences explored jun kaplan luciferase mdm2 meier microarray micrornas mir mirna mirnas multistep noncancerous numerous obstacles obviously reporter serve tnm tumorigenesis	adenomatous arhgap causative cntn6 cnv cnvs ctnnb1 etiologically filtered focad german germline hsph1 kiaa1797 mcm3ap mining mutyh ngs nonrecurrent polyposis predispose predisposition prioritized silico stringent truncating uncover unexplained ybey
Tagcloud (Intersection) ?