LONRF1 and EFHC2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LONRF1	EFHC2
Gene Name		LON peptidase N-terminal domain and ring finger 1	EF-hand domain (C-terminal) containing 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	ATP-dependent Peptidase Activity Zinc Ion Binding	Calcium Ion Binding
	Biological Process	Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ADAMTSL4 ALAS1 ATG9A BRCA1 BYSL CALCOCO2 CCDC36 CRX EFHC2 GORASP1 GORASP2 IKZF2 IQCF2 KAT5 KCTD9 KRT31 KRTAP13-1 LHX4 NR4A1 PLSCR1 RBPMS SFN SPRY2 STAU1 STX11 TRIM42 TRIM9 UBE2L6 UCHL3 USP2 WDYHV1 XIAP	30 interactors: ARHGEF5 ARMC7 CCDC120 CCHCR1 CCNG2 CLIC3 COPE CYFIP1 DGCR6 EDC3 EGLN3 EMD EXOC8 JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 PBLD PLOD3 PTK6 RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4
Entrez ID		91694	80258
HPRD ID		08674	06540
Ensembl ID		ENSG00000154359
Uniprot IDs		Q17RB8	Q5JST6
PDB IDs			2Z13 2Z14
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Acetylation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Protein Catabolic Process Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Apoptotic Process Cell Death Death Negative Regulation Of Hydrolase Activity Androgen Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Gene Expression Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Photoreceptor Cell Differentiation Positive Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Synaptic Vesicle Exocytosis Regulation Of Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Medial Motor Column Neuron Differentiation Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of SNARE Complex Assembly Positive Regulation Of Protein Linear Polyubiquitination Late Nucleophagy Piecemeal Microautophagy Of Nucleus Negative Regulation Of Protein Metabolic Process Response To Stress Positive Regulation Of Transcription, DNA-templated Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Viral Genome Replication	Regulation Of Podosome Assembly
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