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LONRF1 and SFN
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
LONRF1
SFN
Gene Name
LON peptidase N-terminal domain and ring finger 1
stratifin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Cytoplasmic Vesicle Membrane
Extracellular Vesicular Exosome
Molecular Function
ATP-dependent Peptidase Activity
Zinc Ion Binding
Protein Binding
Protein Kinase C Inhibitor Activity
Protein Kinase Binding
Protein Domain Specific Binding
Phosphoprotein Binding
Biological Process
Proteolysis
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Release Of Cytochrome C From Mitochondria
Keratinocyte Development
Negative Regulation Of Protein Kinase Activity
Apoptotic Process
Signal Transduction
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Epidermal Cell Division
Negative Regulation Of Keratinocyte Proliferation
Positive Regulation Of Cell Growth
Keratinization
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Epidermal Cell Differentiation
Positive Regulation Of Protein Export From Nucleus
Membrane Organization
Establishment Of Skin Barrier
Negative Regulation Of Protein Serine/threonine Kinase Activity
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
Activation of BAD and translocation to mitochondria
Programmed Cell Death
Translocation of GLUT4 to the plasma membrane
Activation of BH3-only proteins
Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions
32 interactors:
ADAMTSL4
ALAS1
ATG9A
BRCA1
BYSL
CALCOCO2
CCDC36
CRX
EFHC2
GORASP1
GORASP2
IKZF2
IQCF2
KAT5
KCTD9
KRT31
KRTAP13-1
LHX4
NR4A1
PLSCR1
RBPMS
SFN
SPRY2
STAU1
STX11
TRIM42
TRIM9
UBE2L6
UCHL3
USP2
WDYHV1
XIAP
49 interactors:
ABL1
BAD
BAX
BCR
CCAR1
CCDC102B
CCNH
CDC25B
CDK1
CHST1
EEF1A1
EGFR
EIF2S1
EIF4B
EXO1
FAM189A2
FAM53C
FAM9B
FOXO4
GPRIN2
HDAC5
HNRNPD
ING1
KCNK15
KCNK3
KCNK9
KIAA0408
LONRF1
MAGEA1
MAP3K5
MARK3
MDM4
MKRN3
MST1R
NR3C1
PLEKHF2
PLK4
RAB3IP
RFFL
RFWD2
SAMSN1
TBL3
TP53
TRIM25
TSC2
WDYHV1
YWHAG
ZC2HC1C
ZFP36
Entrez ID
91694
2810
HPRD ID
08674
03185
Ensembl ID
ENSG00000154359
ENSG00000175793
Uniprot IDs
Q17RB8
P31947
PDB IDs
1YWT
1YZ5
3IQJ
3IQU
3IQV
3LW1
3MHR
3O8I
3P1N
3P1O
3P1P
3P1Q
3P1R
3P1S
3SMK
3SML
3SMM
3SMN
3SMO
3SPR
3T0L
3T0M
3U9X
3UX0
4DAT
4DAU
4DHM
4DHN
4DHO
4DHP
4DHQ
4DHR
4DHS
4DHT
4DHU
4FR3
4HQW
4HRU
4IEA
4JC3
4JDD
Enriched GO Terms of Interacting Partners
?
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
DNA Damage Response, Signal Transduction Resulting In Transcription
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity
Modification-dependent Protein Catabolic Process
Positive Regulation Of Protein Acetylation
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Protein Catabolic Process
Apoptotic Process
Negative Regulation Of Cell Death
Programmed Cell Death
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Apoptotic Process
Cell Death
Death
Negative Regulation Of Hydrolase Activity
Androgen Receptor Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Gene Expression
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cell Death
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Positive Regulation Of Photoreceptor Cell Differentiation
Positive Regulation Of Cellular Metabolic Process
Intracellular Receptor Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Innate Immune Response
Negative Regulation Of Cellular Protein Metabolic Process
Synaptic Vesicle Exocytosis
Regulation Of Protein Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Medial Motor Column Neuron Differentiation
Positive Regulation Of Histone H3-K9 Acetylation
Negative Regulation Of SNARE Complex Assembly
Positive Regulation Of Protein Linear Polyubiquitination
Late Nucleophagy
Piecemeal Microautophagy Of Nucleus
Negative Regulation Of Protein Metabolic Process
Response To Stress
Positive Regulation Of Transcription, DNA-templated
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Viral Genome Replication
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Neuron Death
Cell Cycle
Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Phosphorylation
Cellular Response To Organic Substance
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Kinase Activity
Cellular Response To Organonitrogen Compound
Regulation Of Phosphorus Metabolic Process
Cell Cycle Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Intracellular Transport
Mitotic Cell Cycle Process
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Intracellular Signal Transduction
ERBB Signaling Pathway
Regulation Of Protein Kinase Activity
Response To Stress
Mitotic Cell Cycle
Positive Regulation Of Cell Cycle
Response To Organic Substance
Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Cell Cycle
Positive Regulation Of Protein Metabolic Process
Cellular Response To Stress
Cellular Response To DNA Damage Stimulus
Regulation Of Catalytic Activity
Cellular Response To Insulin Stimulus
G2/M Transition Of Mitotic Cell Cycle
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Negative Regulation Of Mitotic Cell Cycle
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Mitochondrion Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Response To Hormone
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
Regulation Of Intracellular Signal Transduction
Cellular Response To Hormone Stimulus
Regulation Of Cell Proliferation
B Cell Activation
Fc Receptor Signaling Pathway
Tagcloud
?
aging
alarm
amplitude
auditory
circuits
cortico
elderly
electrophysiologically
employed
false
finding
frontal
impairments
latency
limbic
memory
n4
p3
perform
position
potentials
prefrontal
recency
serial
sternberg
subjects
task
working
young
Tagcloud (Difference)
?
aging
alarm
amplitude
auditory
circuits
cortico
elderly
electrophysiologically
employed
false
finding
frontal
impairments
latency
limbic
memory
n4
p3
perform
position
potentials
prefrontal
recency
serial
sternberg
subjects
task
working
young
Tagcloud (Intersection)
?