EFHC2 and KIF9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EFHC2	KIF9
Gene Name		EF-hand domain (C-terminal) containing 2	kinesin family member 9
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Gene Ontology Annotations	Cellular Component		Podosome Cytoplasm Kinesin Complex Microtubule Vesicle
	Molecular Function	Calcium Ion Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Dimerization Activity
	Biological Process		Microtubule-based Movement Blood Coagulation Metabolic Process Extracellular Matrix Disassembly Regulation Of Podosome Assembly Organelle Disassembly
Pathways			Kinesins Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: ARHGEF5 ARMC7 CCDC120 CCHCR1 CCNG2 CLIC3 COPE CYFIP1 DGCR6 EDC3 EGLN3 EMD EXOC8 JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 PBLD PLOD3 PTK6 RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4	13 interactors: CARD9 EFHC2 IKZF1 JAKMIP2 KRTAP10-3 KRTAP10-9 LZTS2 PRMT6 ROPN1 SSX2IP TRIM27 TRIM37 ZBTB8A
Entrez ID		80258	64147
HPRD ID		06540	07444
Ensembl ID			ENSG00000088727
Uniprot IDs		Q5JST6	A8K932 Q9HAQ2
PDB IDs		2Z13 2Z14	3NWN
Enriched GO Terms of Interacting Partners?		Regulation Of Podosome Assembly	Organelle Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone H3-R2 Methylation Negative Regulation Of Interleukin-2 Secretion Chromatin Modification Histone H2A-K119 Monoubiquitination Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Centriole Replication Negative Regulation Of Calcium Ion Import Intraciliary Transport Involved In Cilium Morphogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Positive Regulation Of NK T Cell Differentiation Interferon-gamma Secretion Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromosome Organization Regulation Of Centriole Replication Histone H2A Monoubiquitination Aggresome Assembly Regulation Of Cellular Process Response To Peptidoglycan Microtubule Severing Transcription, DNA-templated Histone H4-R3 Methylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cytoskeleton Organization RNA Biosynthetic Process Negative Regulation Of Viral Release From Host Cell Histone H2A Ubiquitination Negative Regulation Of Centrosome Duplication Peptidyl-arginine N-methylation Lymph Node Development Peyer's Patch Development Regulation Of Transcription, DNA-templated Regulation Of Tumor Necrosis Factor Biosynthetic Process Response To Muramyl Dipeptide Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
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