LONRF1 and PPP1R3C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LONRF1	PPP1R3C
Description		LON peptidase N-terminal domain and ring finger 1	protein phosphatase 1 regulatory subunit 3C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Protein Phosphatase Type 1 Complex Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Serine/threonine Phosphatase Activity Protein Binding Protein Phosphatase 1 Binding Protein Phosphatase Binding Molecular Adaptor Activity Glycogen Binding
	Biological Process		Glycogen Metabolic Process Glycogen Biosynthetic Process Regulation Of Glycogen Biosynthetic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Colorectal cancer (diet interaction) ( 24743840) HDL cholesterol levels ( 32203549)
Interacting Genes		98 interacting genes: ADAMTSL4 ALAS1 AP2B1 ATG9A AVPI1 BRCA1 BYSL C4orf17 CALCOCO2 CBLL2 CDKN2D CFP CRX CYSRT1 DSCR9 DVL3 EFHC2 FLACC1 GABPB2 GORASP1 GORASP2 GPRASP3 HLX HOXA1 HSPB1 IHO1 IKZF2 IKZF3 IQCF2 KAT5 KATNBL1 KCTD21 KCTD9 KHDC1 KRT31 KRT35 KRT75 KRTAP1-3 KRTAP13-1 KRTAP13-3 KRTAP19-6 KRTAP19-7 KRTAP3-3 KRTAP6-1 LGALS9B LHX2 LHX4 LNX1 MAGED1 MGAT5B MID2 MRPL38 MTMR3 MYOZ3 NR4A1 NTAQ1 OOEP PATZ1 PAX5 PAX6 PAX8 PICK1 PLSCR1 POU6F2 PPP1R3C PRDM16 PRDM6 PRR35 PSMA1 RBPMS RIMBP3C RPRD1A RSPH1 SFN SLU7 SPRY2 STAU1 STX11 TASOR2 TBX19 TRAF2 TRIM27 TRIM42 TRIM8 TRIM9 UBE2I UBE2L6 UCHL3 USP2 VGLL1 WDR83 XIAP YPEL3 ZFP90 ZNF426 ZNF653 ZNF774 ZNHIT2	10 interacting genes: APP EPM2A LONRF1 LXN NHLRC1 PPP1CA PPP1CB PPP1CC PRKAB2 SGTA
Entrez ID		91694	5507
HPRD ID		08674	04298
Ensembl ID		ENSG00000154359	ENSG00000119938
Uniprot IDs		Q17RB8	Q9UQK1
PDB IDs			7QF7 7QFA 7QFB 7QM2
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Zinc Ion Binding Protein Modification By Small Protein Conjugation Protein Ubiquitination Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Identical Protein Binding Keratin Filament Post-translational Protein Modification Positive Regulation Of RNA Metabolic Process Ubiquitin Protein Ligase Activity Regulation Of DNA-templated Transcription Transcription Coactivator Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Protein Kinase C Inhibitor Activity Negative Regulation Of Viral Transcription Suppression Of Viral Release By Host Positive Regulation Of Biosynthetic Process Regulation Of Viral Transcription Regulation Of RNA Metabolic Process Protein Modification Process Establishment Of Spindle Localization Structural Constituent Of Skin Epidermis RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Spindle Localization Non-canonical Inflammasome Complex Assembly Telencephalon Regionalization Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Cellular Response To Vascular Endothelial Growth Factor Stimulus Outer Dense Fiber Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Cytosol Protein K63-linked Ubiquitination Negative Regulation Of Viral Process Positive Regulation Of Macromolecule Metabolic Process Nucleus	Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process PTW/PP1 Phosphatase Complex Energy Derivation By Oxidation Of Organic Compounds Phosphatase Activity Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Dephosphorylation Generation Of Precursor Metabolites And Energy Phosphoprotein Phosphatase Activity Carbohydrate Metabolic Process Circadian Regulation Of Gene Expression Protein Metabolic Process Response To Light Stimulus Regulation Of Circadian Rhythm Glycogen Biosynthetic Process Response To Lead Ion Transition Metal Ion Binding Circadian Rhythm Polysaccharide Biosynthetic Process Perikaryon Protein Phosphatase 1 Binding Dendritic Spine Response To Radiation Chromosome, Telomeric Region Protein Kinase Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Amyloid-beta Complex Presynapse Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Hydrolase Activity Myosin-light-chain-phosphatase Activity Carbohydrate Phosphatase Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Rhythmic Process Cytosol Positive Regulation Of Gliogenesis Regulation Of Carbohydrate Catabolic Process Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import
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