LONRF1 and CCDC36

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LONRF1	CCDC36
Gene Name		LON peptidase N-terminal domain and ring finger 1	coiled-coil domain containing 36
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	ATP-dependent Peptidase Activity Zinc Ion Binding
	Biological Process	Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ADAMTSL4 ALAS1 ATG9A BRCA1 BYSL CALCOCO2 CCDC36 CRX EFHC2 GORASP1 GORASP2 IKZF2 IQCF2 KAT5 KCTD9 KRT31 KRTAP13-1 LHX4 NR4A1 PLSCR1 RBPMS SFN SPRY2 STAU1 STX11 TRIM42 TRIM9 UBE2L6 UCHL3 USP2 WDYHV1 XIAP	33 interactors: ABI2 AQP1 C1orf109 CARD9 CDC23 COX5B DGCR6 DYNLL1 DYNLL2 FAM124A FANCL FKBP6 GYS1 HEXIM2 IQUB KANK2 KLC3 LMO2 LONRF1 MRFAP1L1 MVP MYO15B NEK6 NGB POLR1C PRKAB2 RUNX1T1 SDCBP STK25 TRIM42 TTC19 USP2 USP20
Entrez ID		91694	339834
HPRD ID		08674	14172
Ensembl ID		ENSG00000154359	ENSG00000173421
Uniprot IDs		Q17RB8	B4DZP6 Q8IYA8
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Acetylation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Protein Catabolic Process Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Apoptotic Process Cell Death Death Negative Regulation Of Hydrolase Activity Androgen Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Gene Expression Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Photoreceptor Cell Differentiation Positive Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Synaptic Vesicle Exocytosis Regulation Of Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Medial Motor Column Neuron Differentiation Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of SNARE Complex Assembly Positive Regulation Of Protein Linear Polyubiquitination Late Nucleophagy Piecemeal Microautophagy Of Nucleus Negative Regulation Of Protein Metabolic Process Response To Stress Positive Regulation Of Transcription, DNA-templated Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Viral Genome Replication	Regulation Of Proteasomal Protein Catabolic Process Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Organelle Organization Organelle Organization Regulation Of Cell Cycle Regulation Of Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Cycle Regulation Of Proteolysis Regulation Of Protein Catabolic Process Ammonium Transmembrane Transport Positive Regulation Of Organelle Organization Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Synaptic Target Recognition Regulation Of Mitotic Cell Cycle Regulation Of Phosphorus Metabolic Process Generation Of Precursor Metabolites And Energy Regulation Of Stress-activated MAPK Cascade Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Mitochondrion Organization Cellular Response To Hydrogen Peroxide Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Vitamin D Receptor Signaling Pathway Carbon Dioxide Transmembrane Transport Corticotropin Secretion Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Cell Cycle Phase Transition Positive Regulation Of Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ammonium Transport Proteasomal Protein Catabolic Process
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