LONRF1 and CRX

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LONRF1	CRX
Gene Name		LON peptidase N-terminal domain and ring finger 1	cone-rod homeobox
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Transcription Factor Complex
	Molecular Function	ATP-dependent Peptidase Activity Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding
	Biological Process	Proteolysis	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Visual Perception Circadian Rhythm Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Photoreceptor Cell Differentiation Response To Stimulus Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ADAMTSL4 ALAS1 ATG9A BRCA1 BYSL CALCOCO2 CCDC36 CRX EFHC2 GORASP1 GORASP2 IKZF2 IQCF2 KAT5 KCTD9 KRT31 KRTAP13-1 LHX4 NR4A1 PLSCR1 RBPMS SFN SPRY2 STAU1 STX11 TRIM42 TRIM9 UBE2L6 UCHL3 USP2 WDYHV1 XIAP	44 interactors: ABI2 AES ATG12 ATXN7 BANF1 C1orf109 C9orf72 CA8 CCNC CREBBP CSNK1G2-AS1 EIF5A EP300 GCM2 GUCD1 IPO13 KAT2A KIAA0141 KLHL32 LARP4 LONRF1 M1AP MDFI MLLT6 NIP7 NPAS2 NR2E3 NRL OSGIN1 PARK2 PDC PID1 PPP1R16B PRKAB2 PSMB10 QRICH1 RAX2 RBFOX1 ROR2 SFI1 SOX5 STK16 SZT2 UBXN2B
Entrez ID		91694	1406
HPRD ID		08674	03748
Ensembl ID		ENSG00000154359	ENSG00000105392
Uniprot IDs		Q17RB8	O43186
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Acetylation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Protein Catabolic Process Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Apoptotic Process Cell Death Death Negative Regulation Of Hydrolase Activity Androgen Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Gene Expression Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Photoreceptor Cell Differentiation Positive Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Synaptic Vesicle Exocytosis Regulation Of Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Medial Motor Column Neuron Differentiation Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of SNARE Complex Assembly Positive Regulation Of Protein Linear Polyubiquitination Late Nucleophagy Piecemeal Microautophagy Of Nucleus Negative Regulation Of Protein Metabolic Process Response To Stress Positive Regulation Of Transcription, DNA-templated Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Viral Genome Replication	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Rhodopsin Gene Expression N-terminal Peptidyl-lysine Acetylation Regulation Of Rhodopsin Gene Expression Transcription, DNA-templated Visual Perception Sensory Perception Of Light Stimulus Positive Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Mitochondrial Fusion Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Organelle Organization Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Autophagy N-terminal Protein Amino Acid Acetylation Nuclear Envelope Reassembly Cellular Response To Stimulus Response To Stimulus Negative Regulation Of Wnt Signaling Pathway Cellular Metabolic Process Somitogenesis Cellular Nitrogen Compound Metabolic Process Developmental Process Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Histone Deubiquitination Neurological System Process Somite Development Cellular Response To Stress Regulation Of Type I Interferon Production Peptidyl-amino Acid Modification Peptidyl-lysine Modification Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Tagcloud ?			5sa aspect cofactor embryos exit hippo lats1 morphogenesis mst1 mst2 neurogenesis orchestrate otx5 phosphorylate photoreceptor pigmentation playing progenitor prolongs remarkably repressing retinal retinogenesis rhodopsin rx1 tead ww yap zebrafish
Tagcloud (Difference) ?			5sa aspect cofactor embryos exit hippo lats1 morphogenesis mst1 mst2 neurogenesis orchestrate otx5 phosphorylate photoreceptor pigmentation playing progenitor prolongs remarkably repressing retinal retinogenesis rhodopsin rx1 tead ww yap zebrafish
Tagcloud (Intersection) ?