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EFHC2 and ARHGEF5
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
EFHC2
ARHGEF5
Gene Name
EF-hand domain (C-terminal) containing 2
Rho guanine nucleotide exchange factor (GEF) 5
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Molecular Function
Calcium Ion Binding
Rho Guanyl-nucleotide Exchange Factor Activity
Protein Binding
GTP Binding
Biological Process
Myeloid Dendritic Cell Chemotaxis
Actin Cytoskeleton Organization
Regulation Of Rho GTPase Activity
Positive Regulation Of Rho GTPase Activity
Intracellular Signal Transduction
Positive Regulation Of Podosome Assembly
Pathways
Drugs
Diseases
GWAS
Breast cancer (
23535729
)
Protein-Protein Interactions
30 interactors:
ARHGEF5
ARMC7
CCDC120
CCHCR1
CCNG2
CLIC3
COPE
CYFIP1
DGCR6
EDC3
EGLN3
EMD
EXOC8
JAKMIP2
KIF9
LONRF1
MAPK9
NCDN
NCK2
NDOR1
PBLD
PLOD3
PTK6
RUNX1T1
SNRNP25
SPG21
STK16
TRIM42
TSSK3
TUBGCP4
15 interactors:
APP
ATP13A1
CALCOCO2
CCNE1
CHPF
CRKL
EFHC2
FKBP8
GRB2
HSPBAP1
NR4A1
PLCG1
SEPHS2
TRIM27
TRIM54
Entrez ID
80258
7984
HPRD ID
06540
02932
Ensembl ID
ENSG00000050327
Uniprot IDs
Q5JST6
Q12774
PDB IDs
2Z13
2Z14
Enriched GO Terms of Interacting Partners
?
Regulation Of Podosome Assembly
Innate Immune Response
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Protein Kinase Activity
Immune Response
Regulation Of Phosphorylation
Defense Response
Regulation Of Kinase Activity
Immune System Process
Regulation Of Phosphorus Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Intracellular Receptor Signaling Pathway
Viral Process
Regulation Of Protein Phosphorylation
Cellular Response To Growth Factor Stimulus
Fc-epsilon Receptor Signaling Pathway
Chemotaxis
Response To Growth Factor
Regulation Of Cellular Protein Metabolic Process
Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Fc Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Selenocysteine Biosynthetic Process
Activation Of MAPKK Activity
Signaling
Cell Communication
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of ERBB Signaling Pathway
Regulation Of Immune Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Response To Stress
Enzyme Linked Receptor Protein Signaling Pathway
Axon Guidance
Negative Regulation Of Interleukin-2 Secretion
Synaptic Growth At Neuromuscular Junction
Selenium Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Blood Coagulation
Hemostasis
Positive Regulation Of Actin Filament Polymerization
Collateral Sprouting In Absence Of Injury
Immune Response-regulating Signaling Pathway
Positive Regulation Of Protein Polymerization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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