LONRF1 and TRIM42

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LONRF1	TRIM42
Gene Name		LON peptidase N-terminal domain and ring finger 1	tripartite motif containing 42
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Intracellular
	Molecular Function	ATP-dependent Peptidase Activity Zinc Ion Binding	Zinc Ion Binding
	Biological Process	Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ADAMTSL4 ALAS1 ATG9A BRCA1 BYSL CALCOCO2 CCDC36 CRX EFHC2 GORASP1 GORASP2 IKZF2 IQCF2 KAT5 KCTD9 KRT31 KRTAP13-1 LHX4 NR4A1 PLSCR1 RBPMS SFN SPRY2 STAU1 STX11 TRIM42 TRIM9 UBE2L6 UCHL3 USP2 WDYHV1 XIAP	63 interactors: ADAMTSL4 ARMC7 ARNT2 ARRDC3 BEX2 C1orf109 CARD9 CCDC33 CCDC36 CDCA7L CEP70 EFHC2 EMD FAM103A1 FAM208B GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NL PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RCOR3 RUNX1T1 SCNM1 SPERT SSX2IP STK16 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1
Entrez ID		91694	287015
HPRD ID		08674	15559
Ensembl ID		ENSG00000154359	ENSG00000155890
Uniprot IDs		Q17RB8	Q8IWZ5
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Acetylation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Protein Catabolic Process Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Apoptotic Process Cell Death Death Negative Regulation Of Hydrolase Activity Androgen Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Gene Expression Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Photoreceptor Cell Differentiation Positive Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Synaptic Vesicle Exocytosis Regulation Of Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Medial Motor Column Neuron Differentiation Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of SNARE Complex Assembly Positive Regulation Of Protein Linear Polyubiquitination Late Nucleophagy Piecemeal Microautophagy Of Nucleus Negative Regulation Of Protein Metabolic Process Response To Stress Positive Regulation Of Transcription, DNA-templated Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Viral Genome Replication	Gene Expression Regulation Of Apoptotic Process Cell Death Regulation Of Cell Death Death RNA Metabolic Process Transcription, DNA-templated Regulation Of Canonical Wnt Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Wnt Signaling Pathway Protein Polyubiquitination Regulation Of Signaling Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Viral Release From Host Cell Regulation Of Signal Transduction Apoptotic Process Negative Regulation Of Viral Process Positive Regulation Of Ligase Activity Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Cellular Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Gene Expression Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Protein Modification By Small Protein Conjugation Temperature Homeostasis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Protein K63-linked Ubiquitination Regulation Of Metabolic Process Protein Trimerization Positive Regulation Of Pro-T Cell Differentiation Abducens Nerve Formation Negative Regulation Of Locomotion Involved In Locomotory Behavior Optokinetic Behavior Negative Regulation Of Heat Generation Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Positive Regulation Of Protein Ubiquitination Positive Regulation Of Signal Transduction
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