ARHGEF1 |
ATR |
||
---|---|---|---|
Gene Name | Rho guanine nucleotide exchange factor (GEF) 1 | ATR serine/threonine kinase | |
Image | No pdb structure | ||
Gene Ontology Annotations | Cellular Component | ||
Molecular Function | |||
Biological Process |
|
||
Pathways | |||
Drugs | |||
Diseases | |||
GWAS | |||
Protein-Protein Interactions | 11 interactors: ATR CD44 CNKSR1 CSNK1E GNA13 HRAS PRKCA RAP1A RHOA SREBF2 TCF4 | 47 interactors: AATF ABL1 AP1B1 AP2A2 ARHGEF1 ATM ATRIP BLM BRCA1 BRCA2 CDKN2C CEP164 CHD4 CHEK1 CHEK2 CLSPN CREB1 DCLRE1C DTL E2F1 E4F1 EEF1E1 EP300 FANCA FANCD2 FLT1 H2AFX KDR LIG4 MCM2 MRE11A MSH2 NBN PA2G4 PIK3CA POLD1 POLN PPP2R2A PTS RAD17 RHEB TP53 TREX1 UPF1 VPRBP XPA XRCC5 | |
Entrez ID | 9138 | 545 | |
HPRD ID | 03511 | 08369 | |
Ensembl ID | ENSG00000076928 | ENSG00000175054 | |
Uniprot IDs | Q6NX52 Q92888 | Q13535 | |
PDB IDs | 1IAP 1SHZ 3AB3 3ODO 3ODW 3ODX 3P6A | ||
Enriched GO Terms of Interacting Partners? |
|
|
|
Tagcloud ? | activates
angiotensin
arterial
arteries
causative
elusive
environmental
exchange
feature
frequent
guanine
hypertension
ii
inactivation
industrialized
monomeric
muscle
pathologies
phosphorylates
recognized
remains
responsible
rhoa
smooth
specifically
tyr738
unclear
undescribed
world
|
activators
breakage
broad
chromatin
chromosome
comprises
concept
defect
discuss
emerging
exert
heterochromatin
hybrid
inherited
mediate
member
modulating
mr
numerous
observations
remodelling
repair
retardation
seems
segregation
snf2
somehow
thalaessemia
xnp
|
|
Tagcloud (Difference) ? | activates
angiotensin
arterial
arteries
causative
elusive
environmental
exchange
feature
frequent
guanine
hypertension
ii
inactivation
industrialized
monomeric
muscle
pathologies
phosphorylates
recognized
remains
responsible
rhoa
smooth
specifically
tyr738
unclear
undescribed
world
|
activators
breakage
broad
chromatin
chromosome
comprises
concept
defect
discuss
emerging
exert
heterochromatin
hybrid
inherited
mediate
member
modulating
mr
numerous
observations
remodelling
repair
retardation
seems
segregation
snf2
somehow
thalaessemia
xnp
|
|
Tagcloud (Intersection) ? |