GIPC2 and PTN

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GIPC2	PTN
Gene Name		GIPC PDZ domain containing family, member 2	pleiotrophin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Extracellular Space Endoplasmic Reticulum
	Molecular Function	Molecular_function	Protein Phosphatase Inhibitor Activity Growth Factor Activity Heparin Binding
	Biological Process	Biological_process	Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Nervous System Development Learning Positive Regulation Of Cell Proliferation Bone Mineralization Negative Regulation Of Catalytic Activity Positive Regulation Of Cell Division
Pathways
Drugs
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		7 interactors: FZD3 IGSF21 PTN SETDB1 SP100 UNC119 ZBTB26	97 interactors: ACTB ALK APOBEC3G ARIH2 ARL15 ATP5C1 ATRX BAG6 BARD1 BCCIP BCL2L1 BLOC1S1 BMI1 BTBD2 C11orf58 C7orf25 CAAP1 CACNB4 CAPZB CCDC53 CDH10 CDK5RAP2 CGA CHD3 COX6C CRCT1 CRELD1 CSTA CYP2E1 DFNA5 DNAJB11 DUSP12 EIF3F EVA1A FEZ1 FTL GADD45A GADD45G GIPC2 GLYAT GNB2L1 GPD1 GPRASP2 GSK3B GSTP1 GTF2F1 HGH1 HSPBAP1 ITSN2 KPNB1 LAMA4 LUC7L2 MAD2L1BP MKKS MLLT3 MRPL44 MYCBP NAP1L5 NCAN NEK6 NUDT21 P4HB PFDN1 PIAS4 PLXNB2 PMF1 PPP2CA PSMB10 PSMD11 PSMD2 PTPRS PTPRZ1 RBM23 RIT1 RPLP1 SAT1 SDC1 SDC3 SGSM2 SGTA SLC25A36 SNCAIP SPIN1 SSR1 STC2 SUPT7L TAC3 TAF1D TBRG4 TOMM20 TP53BP2 TSC22D1 TXNDC9 UBQLN1 UBQLN4 UTP3 WFDC2
Entrez ID		54810	5764
HPRD ID		17040	01199
Ensembl ID			ENSG00000105894
Uniprot IDs		Q8TF65	P21246
PDB IDs		3GGE
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Clathrin-mediated Endocytosis Cell Proliferation In Midbrain Negative Regulation Of Mitotic Cell Cycle, Embryonic Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Fas Signaling Pathway Cytokinesis, Completion Of Separation Regulation Of Mitotic Cell Cycle, Embryonic Negative Regulation Of Protein Export From Nucleus Regulation Of Caveolin-mediated Endocytosis Learning Or Memory Mitotic Cytokinetic Process Negative Regulation Of Execution Phase Of Apoptosis Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Neurological System Process Cognition Histone H3-K9 Trimethylation	Cell Cycle Nitrogen Compound Metabolic Process Apoptotic Process Central Nervous System Development Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process Programmed Cell Death Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Cell Death Regulation Of Cell Cycle Death Regulation Of Protein Catabolic Process Negative Regulation Of Transferase Activity Response To Endoplasmic Reticulum Stress Regulation Of Cell Death Regulation Of Cellular Process Signal Transduction By P53 Class Mediator Cell Cycle Process Negative Regulation Of Cell Cycle Positive Regulation Of Transferase Activity Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Brain Development Nervous System Development Regulation Of Intrinsic Apoptotic Signaling Pathway Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Modification Process Viral Process Developmental Process Head Development Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Multicellular Organismal Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Process Heterocycle Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Signaling Cellular Response To Stress Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity
Tagcloud ?		adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc1 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2	04fmolt4 04mg 09mg 28ng 32ng 37g 58vo2ml 64g 71ng 94ng 99mg backgrounds bat carioca chf corticosterone ctrl d2 depot endocrine epididymal freezing glycemia impair kg0 retroperitoneal t4 triglycerides weights
Tagcloud (Difference) ?		adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc1 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2	04fmolt4 04mg 09mg 28ng 32ng 37g 58vo2ml 64g 71ng 94ng 99mg backgrounds bat carioca chf corticosterone ctrl d2 depot endocrine epididymal freezing glycemia impair kg0 retroperitoneal t4 triglycerides weights
Tagcloud (Intersection) ?