GIPC2 and ZBTB26

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		GIPC2	ZBTB26
Description		GIPC PDZ domain containing family member 2	zinc finger and BTB domain containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Body mass index ( 29273807) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) End-stage kidney disease ( 31178898) Hand grip strength ( 29691431) Height ( 20881960 25282103) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean corpuscular hemoglobin concentration ( 32888494) Platelet distribution width ( 32888494) Post bronchodilator FEV1 ( 26634245) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Severe influenza A (H1N1) infection ( 26379185)	Appendicular lean mass ( 33097823) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: CTRC FZD3 IGSF21 IRF4 LZTS2 PATJ PLEKHA2 PTN SETDB1 SP100 UBE2I UNC119 ZBTB26 ZCCHC7	35 interacting genes: AXIN1 CARD10 CDC37 CDC7 CYP2W1 DAXX DRC4 DVL3 EHHADH EIF6 GIPC2 HMBOX1 L3MBTL2 LNX1 MORF4L1 MORF4L2 PBK PPL RAD23A RAD54L2 RNF4 SOX5 SUMO1 SUMO1P1 TRAF4 TRIM41 TSGA10 UBE2I ZBTB12 ZBTB34 ZBTB48 ZBTB6 ZBTB9 ZMYM5 ZNF408
Entrez ID		54810	57684
HPRD ID		17040	15692
Ensembl ID		ENSG00000137960	ENSG00000171448
Uniprot IDs		A0A384P5H2 Q8TF65	Q9HCK0
PDB IDs		3GGE
Enriched GO Terms of Interacting Partners?			Regulation Of Primary Metabolic Process PML Body Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Transcription Factor Binding Nucleus Small Protein Activating Enzyme Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process PML Body Organization Nuclear Body Enzyme Binding Double-stranded Telomeric DNA Binding Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Sumoylation Zinc Ion Binding Negative Regulation Of RNA Metabolic Process Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Tag Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Identical Protein Binding Positive Regulation Of Metabolic Process DNA Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nuclear Body Organization Positive Regulation Of Macromolecule Metabolic Process Ubiquitin-specific Protease Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Cadmium Ion Regulation Of Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Ubiquitin-like Protein Ligase Binding NuA4 Histone Acetyltransferase Complex Presynaptic Cytosol Response To Arsenic-containing Substance Postsynaptic Cytosol Positive Regulation Of Proteasomal Protein Catabolic Process
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