RCC1 and SPRED1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RCC1	SPRED1
Gene Name		regulator of chromosome condensation 1	sprouty-related, EVH1 domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane	Nucleoplasm Cytoplasm Caveola
	Molecular Function	Chromatin Binding Ran Guanyl-nucleotide Exchange Factor Activity Protein Binding Nucleosomal DNA Binding Histone Binding	Stem Cell Factor Receptor Binding Protein Binding Protein Kinase Binding Phosphatase Binding Protein Serine/threonine Kinase Inhibitor Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Viral Process Positive Regulation Of Ran GTPase Activity Spindle Assembly Cell Division	Inactivation Of MAPK Activity Multicellular Organismal Development Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Phosphatase Activity Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Protein Deacetylation
Pathways		HIV Life Cycle Rev-mediated nuclear export of HIV RNA HIV Infection Nuclear import of Rev protein Rev-mediated nuclear export of HIV RNA Host Interactions of HIV factors Interactions of Rev with host cellular proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Crohn's disease ( 23128233) Hypersomnia (HLA-DQB1*06:02 negative) ( 23646285)
Protein-Protein Interactions		50 interactors: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 FAF1 FLAD1 GNB2 HADHB HIST1H3A HIST1H4A HIST2H2AA3 HIST2H2AC HIST2H2BE HMGA1 HOXD8 KMT2B KPNA3 KPNA4 KPNB1 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 TLE1 TP53 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135	11 interactors: CDKN1A DNAJB11 FAM118B KIT NAGK OSGEP PPP1CA RCC1 SUV39H1 TSC22D1 TTC19
Entrez ID		1104	161742
HPRD ID		01559	11601
Ensembl ID		ENSG00000180198	ENSG00000166068
Uniprot IDs		P18754 Q5T081	Q7Z699
PDB IDs		1A12 1I2M	3SYX
Enriched GO Terms of Interacting Partners?		Protein Localization To Nucleus Protein Import Into Nucleus Nuclear Import Intracellular Transport Of Virus Protein Localization To Organelle Protein Import Nucleocytoplasmic Transport Nuclear Transport Cell Cycle Mitotic Cell Cycle DNA Packaging Cellular Component Assembly Protein Complex Assembly Cell Cycle Process Chromatin Assembly Cellular Localization Cellular Protein Localization Chromatin Organization NLS-bearing Protein Import Into Nucleus Viral Process Protein Localization Ribosomal Small Subunit Export From Nucleus Chromatin Assembly Or Disassembly DNA Conformation Change Cellular Nitrogen Compound Metabolic Process Chromosome Organization Viral Life Cycle Mitotic Cell Cycle Process Cellular Metabolic Process Positive Regulation Of Cell Aging Establishment Of Protein Localization To Organelle Organelle Organization Establishment Of Protein Localization Ribosomal Large Subunit Export From Nucleus Nitrogen Compound Metabolic Process Intracellular Transport Ribosomal Subunit Export From Nucleus DNA Replication-dependent Nucleosome Assembly Protein Targeting Nucleosome Organization DNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process 'de Novo' Posttranslational Protein Folding Cellular Macromolecular Complex Assembly 'de Novo' Protein Folding Base-excision Repair DNA Methylation On Cytosine Protein Transport Protein-DNA Complex Assembly	Cell Division Cell Cycle Rhythmic Process Response To Light Stimulus Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Mast Cell Proliferation Response To Radiation Response To Abiotic Stimulus Regulation Of Circadian Rhythm Positive Regulation Of Protein Kinase Activity Threonylcarbamoyladenosine Biosynthetic Process Kit Signaling Pathway Erythropoietin-mediated Signaling Pathway N-acetylmannosamine Metabolic Process Positive Regulation Of Kinase Activity Mast Cell Differentiation Positive Regulation Of Transferase Activity Phosphatidylinositol-mediated Signaling Digestive Tract Development Cellular Response To Growth Factor Stimulus Positive Regulation Of Programmed Cell Death Mast Cell Chemotaxis Cellular Response To Erythropoietin N-acetylneuraminate Catabolic Process Response To Growth Factor Digestive System Development Positive Regulation Of Cell Death RNA Modification G1/S Transition Of Mitotic Cell Cycle Threonylcarbamoyladenosine Metabolic Process Intestinal Epithelial Cell Maturation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Catalytic Activity Tube Development Regulation Of Cell Death Cellular Response To Fibroblast Growth Factor Stimulus Melanocyte Migration Histone H3-K9 Dimethylation Positive Regulation Of Protein Phosphorylation Response To Fibroblast Growth Factor Regulation Of Protein Kinase Activity Cellular Response To UV-B Positive Regulation Of Long-term Neuronal Synaptic Plasticity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Ran GTPase Activity Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein
Tagcloud ?		almost cellulose chromosome column condensation consistently cytoplasm digestion dispersed dnase eluted encode kd located locates maturation mitotic nacl nuclei onset p45 prepared presumably putative regulating regulator released sequential synthetic	3g bim bolsters btg3 cdc25a cfue cyclinb1 deployed eaf1 engages epo epor erythroblast erythroblasts gas5 interrogate lyl1 maturing pim1 pim3 presently proerythroblast serpina sf13c socs2 sophisticated tnfr trib3
Tagcloud (Difference) ?		almost cellulose chromosome column condensation consistently cytoplasm digestion dispersed dnase eluted encode kd located locates maturation mitotic nacl nuclei onset p45 prepared presumably putative regulating regulator released sequential synthetic	3g bim bolsters btg3 cdc25a cfue cyclinb1 deployed eaf1 engages epo epor erythroblast erythroblasts gas5 interrogate lyl1 maturing pim1 pim3 presently proerythroblast serpina sf13c socs2 sophisticated tnfr trib3
Tagcloud (Intersection) ?