RCC1 and DDAH2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		RCC1	DDAH2
Description		regulator of chromosome condensation 1	DDAH family member 2, ADMA-independent
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytoplasm Protein-containing Complex	Cytoplasm Mitochondrion Extracellular Exosome
	Molecular Function	DNA Binding Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity	Protein Binding Dimethylargininase Activity Hydrolase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Membrane Reassembly Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Viral Process Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly	Citrulline Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process
Pathways		Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs			Citrulline
Diseases
GWAS		Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		50 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CEBPA CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 LRIF1 NGFR NTMT1 NUDT21 NUP98 OGT PDHB PKM PTMA RAN RANBP1 RANBP3 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135	28 interacting genes: ACTN3 ANXA7 ATP1B1 CDC73 CDK4 CDKN1A DNAJB11 FANCL GADD45G IGFN1 MAP3K20 MKNK1 NOXA1 PIN1 PRKAB2 RAP1B RCC1 RPS6KA1 RPS6KA5 SCGN SMN1 STK3 TAF1D TK1 TNFSF11 TRIP13 TSC22D1 VAC14
Entrez ID		1104	23564
HPRD ID		01559	09204
Ensembl ID		ENSG00000180198	ENSG00000213722
Uniprot IDs		A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081	O95865 V9HW53
PDB IDs		1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB 8UX1
Enriched GO Terms of Interacting Partners?		Chromatin Organization Nucleoplasm Nucleus Chromatin Remodeling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Structural Constituent Of Chromatin Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleosome Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Kinetochore Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Protein Heterodimerization Activity Nuclear Transport Nucleocytoplasmic Transport Nuclear Pore Protein Export From Nucleus Ribosomal Large Subunit Export From Nucleus Chromosome Positive Regulation Of DNA Metabolic Process Ribosomal Small Subunit Export From Nucleus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of DNA Replication Cytosol Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Nuclear Envelope Ribosomal Subunit Export From Nucleus Extracellular Exosome Nuclear Export Nuclear Export Signal Receptor Activity Protein Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteolysis TORC1 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Biosynthetic Process Nuclear Retinoic Acid Receptor Binding Pyruvate Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Protein Localization To Nucleus MRNA Cleavage And Polyadenylation Specificity Factor Complex	Cytoplasm Nucleus Regulation Of Mitotic Cell Cycle Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Kinase Activity Intracellular Signal Transduction Cytosol Regulation Of Cell Cycle Process Protein Kinase Activity JNK Cascade Response To Phorbol 13-acetate 12-myristate Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Positive Regulation Of Programmed Cell Death Epithelial Cell Proliferation Cellular Response To UV-B Protein Phosphorylation Identical Protein Binding Intracellular Signaling Cassette Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Phosphorylation Magnesium Ion Binding Regulation Of Programmed Cell Death Regulation Of Fibroblast Proliferation Negative Regulation Of Cell Cycle Phase Transition Regulation Of Translation In Response To Stress Positive Regulation Of JNK Cascade Response To UV-B Regulation Of Cell Cycle Phase Transition Cellular Response To Gamma Radiation Regulation Of Mitotic Nuclear Division Negative Regulation Of Cell Cycle Process Regulation Of Multicellular Organismal Process Protein Binding Z Disc Phosphate-containing Compound Metabolic Process Signal Transduction Nucleotide Binding ATP Binding Cyclin Binding Regulation Of Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of Nuclear Division Cis-trans Isomerase Activity Positive Regulation Of Apoptotic Process Histone H2AS1 Kinase Activity Positive Regulation Of Mitotic DNA Damage Checkpoint
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