FBLN5 and LPA

Number of citations of the paper that reports this interaction (PMID 12111551)
6

Data Source:
HPRD (in vivo, two hybrid)

		FBLN5	LPA
Gene Name		fibulin 5	lipoprotein, Lp(a)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Elastic Fiber	Extracellular Region Plasma Lipoprotein Particle
	Molecular Function	Integrin Binding Calcium Ion Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity	Fibronectin Binding Serine-type Endopeptidase Activity Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Apolipoprotein Binding
	Biological Process	Regulation Of Cell Growth Cell-matrix Adhesion Extracellular Matrix Organization Protein Localization To Cell Surface Secretion Elastic Fiber Assembly Regulation Of Removal Of Superoxide Radicals	Proteolysis Lipid Metabolic Process Lipid Transport Receptor-mediated Endocytosis Blood Circulation Negative Regulation Of Endopeptidase Activity Lipoprotein Metabolic Process Small Molecule Metabolic Process
Pathways		Molecules associated with elastic fibres Elastic fibre formation
Drugs			Aminocaproic Acid
Diseases
GWAS		Height ( 18391951)	Aortic-valve calcification ( 23388002) Cholesterol, total ( 20686565) Coronary heart disease ( 19198611 21378990) HDL cholesterol ( 20686565) LDL cholesterol ( 20686565) Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302) Lp (a) levels ( 21900290 19124843) Monocyte early outgrowth colony forming units ( 21493818) Protein quantitative trait loci ( 18464913) Response to statin therapy ( 22368281) Response to statin therapy (LDL-C) ( 22331829)
Protein-Protein Interactions		7 interactors: ATN1 GFI1B LOXL1 LPA PAXIP1 SOD3 TOP3B	9 interactors: APOH CANX CELA1 ELANE FBLN5 FGB FN1 LRP2 MMP12
Entrez ID		10516	4018
HPRD ID		05204	01063
Ensembl ID		ENSG00000140092	ENSG00000198670
Uniprot IDs		Q9UBX5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Histone H3-K4 Methylation Regulation Of Histone Methylation Positive Regulation Of Histone H3-K36 Methylation Protein Deamination Regulation Of Histone Modification Regulation Of Chromosome Organization	Extracellular Matrix Organization Extracellular Structure Organization Wound Healing Response To Wounding Extracellular Matrix Disassembly Blood Coagulation Hemostasis Cell-matrix Adhesion Response To Stress Regulation Of Body Fluid Levels Secretion Cell-substrate Adhesion Vesicle-mediated Transport Collagen Catabolic Process Platelet Degranulation Acute Inflammatory Response Collagen Metabolic Process Transport Multicellular Organismal Macromolecule Metabolic Process Inflammatory Response Multicellular Organismal Metabolic Process Secretion By Cell Neutrophil Mediated Killing Of Fungus Protein Metabolic Process Defense Response Triglyceride Transport Response To Stimulus Regulation Of Growth Regulation Of Cell Proliferation Calcium-independent Cell-matrix Adhesion Endocytosis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Pancreas Morphogenesis Negative Regulation Of Chemokine Biosynthetic Process Negative Regulation Of Interleukin-8 Biosynthetic Process Response To Yeast Platelet Activation Elastic Fiber Assembly Negative Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Positive Regulation Of Interleukin-8 Biosynthetic Process Killing By Host Of Symbiont Cells Cell Migration Leukocyte Migration Plasminogen Activation Acute Inflammatory Response To Antigenic Stimulus Exocrine Pancreas Development Negative Regulation Of Locomotion Positive Regulation Of Heterotypic Cell-cell Adhesion Negative Regulation Of Fibrinolysis
Tagcloud ?		5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation	adequacy amplified apl attributable cdna concordance disagreement ensure external hematological hospitals implementation inadequacy laboratories malignancies participating pethema pml promyelocytic rearrangements rr satisfactorily scheme sent spanish standardization standardize stressed supporting
Tagcloud (Difference) ?		5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation	adequacy amplified apl attributable cdna concordance disagreement ensure external hematological hospitals implementation inadequacy laboratories malignancies participating pethema pml promyelocytic rearrangements rr satisfactorily scheme sent spanish standardization standardize stressed supporting
Tagcloud (Intersection) ?