FBLN5 and LOXL1

Number of citations of the paper that reports this interaction (PMID 14745449)
107

Data Source:
BioGRID (pull down, affinity chromatography technology, two hybrid)
HPRD (in vitro, two hybrid, in vivo)

		FBLN5	LOXL1
Gene Name		fibulin 5	lysyl oxidase-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Elastic Fiber	Acrosomal Vesicle Extracellular Region Basement Membrane Extracellular Space Extracellular Matrix
	Molecular Function	Integrin Binding Calcium Ion Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity	Copper Ion Binding Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor
	Biological Process	Regulation Of Cell Growth Cell-matrix Adhesion Extracellular Matrix Organization Protein Localization To Cell Surface Secretion Elastic Fiber Assembly Regulation Of Removal Of Superoxide Radicals	Protein Deamination Extracellular Matrix Organization Response To Lipopolysaccharide Aorta Development Oxidation-reduction Process
Pathways		Molecules associated with elastic fibres Elastic fibre formation	Collagen formation Crosslinking of collagen fibrils Elastic fibre formation Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS		Height ( 18391951)	Aortic root size ( 19584346) Glaucoma (exfoliation) ( 17690259) Height ( 23563607)
Protein-Protein Interactions		7 interactors: ATN1 GFI1B LOXL1 LPA PAXIP1 SOD3 TOP3B	3 interactors: ATXN1 ELN FBLN5
Entrez ID		10516	4016
HPRD ID		05204	08861
Ensembl ID		ENSG00000140092	ENSG00000129038
Uniprot IDs		Q9UBX5	Q08397
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Histone H3-K4 Methylation Regulation Of Histone Methylation Positive Regulation Of Histone H3-K36 Methylation Protein Deamination Regulation Of Histone Modification Regulation Of Chromosome Organization	Extracellular Matrix Organization Extracellular Structure Organization Elastic Fiber Assembly Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Removal Of Superoxide Radicals Stress Fiber Assembly Extracellular Matrix Assembly Protein Localization To Cell Surface
Tagcloud ?		5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation	addressed anterior aqueous capsule cornea deposited elastic elucidation exfoliation extensively fibers fibrillar glaucoma humor immersed intraocular ipe iris lens material meshwork pigment pseudoexfoliation reaches scarce trabecular ultrastructural underneath xfm
Tagcloud (Difference) ?		5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation	addressed anterior aqueous capsule cornea deposited elastic elucidation exfoliation extensively fibers fibrillar glaucoma humor immersed intraocular ipe iris lens material meshwork pigment pseudoexfoliation reaches scarce trabecular ultrastructural underneath xfm
Tagcloud (Intersection) ?