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AP1S2 and AP1G1
Number of citations of the paper that reports this interaction (PMID
22939629
)
44
Data Source:
BioGRID
(two hybrid, two hybrid, biochemical)
HPRD
(two hybrid)
AP1S2
AP1G1
Gene Name
adaptor-related protein complex 1, sigma 2 subunit
adaptor-related protein complex 1, gamma 1 subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Lysosomal Membrane
Cytosol
Coated Pit
AP-type Membrane Coat Adaptor Complex
Cytoplasmic Vesicle Membrane
Trans-Golgi Network Membrane
Golgi Membrane
Cytoplasm
Lysosomal Membrane
Golgi Apparatus
Cytosol
Membrane
AP-type Membrane Coat Adaptor Complex
Clathrin Adaptor Complex
Clathrin-coated Vesicle
Cytoplasmic Vesicle Membrane
Clathrin-coated Vesicle Membrane
Trans-Golgi Network Membrane
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Recycling Endosome
Molecular Function
Protein Transporter Activity
Transporter Activity
Protein Binding
Protein Transporter Activity
Rab GTPase Binding
Kinesin Binding
GTP-dependent Protein Binding
Biological Process
Intracellular Protein Transport
Post-Golgi Vesicle-mediated Transport
Viral Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Regulation Of Defense Response To Virus By Virus
Membrane Organization
Intracellular Protein Transport
Post-Golgi Vesicle-mediated Transport
Viral Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Melanosome Organization
Endosome To Melanosome Transport
Positive Regulation Of Natural Killer Cell Degranulation
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Defense Response To Virus By Virus
Membrane Organization
Golgi To Lysosome Transport
Pathways
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
HIV Infection
Host Interactions of HIV factors
Golgi Associated Vesicle Biogenesis
The role of Nef in HIV-1 replication and disease pathogenesis
Nef mediated downregulation of MHC class I complex cell surface expression
Clathrin derived vesicle budding
Lysosome Vesicle Biogenesis
MHC class II antigen presentation
trans-Golgi Network Vesicle Budding
Adaptive Immune System
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
HIV Infection
Host Interactions of HIV factors
Golgi Associated Vesicle Biogenesis
The role of Nef in HIV-1 replication and disease pathogenesis
Nef mediated downregulation of MHC class I complex cell surface expression
Clathrin derived vesicle budding
Lysosome Vesicle Biogenesis
MHC class II antigen presentation
trans-Golgi Network Vesicle Budding
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
AP1G1
AP1G2
GGA3
20 interactors:
AFTPH
AP1AR
AP1B1
AP1M2
AP1S1
AP1S2
ARF1
CLINT1
CLTC
DNER
KIF13A
MAP1A
RAB5A
RABEP1
RABGEF1
SPTB
SYNRG
SYP
UBL7
ZNF512B
Entrez ID
8905
164
HPRD ID
04636
04637
Ensembl ID
ENSG00000182287
ENSG00000166747
Uniprot IDs
B4DSU4
B7Z3M9
P56377
Q549M9
O43747
Q8IY97
PDB IDs
1IU1
Enriched GO Terms of Interacting Partners
?
Intracellular Protein Transport
Cellular Protein Localization
Protein Transport
Vesicle-mediated Transport
Positive Regulation Of Natural Killer Cell Degranulation
Establishment Of Protein Localization
Intracellular Transport
Golgi To Lysosome Transport
Protein Localization
Establishment Of Localization In Cell
Golgi To Vacuole Transport
Endosome To Melanosome Transport
Pigment Granule Maturation
Cellular Localization
Cellular Pigment Accumulation
Viral Process
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Natural Killer Cell Mediated Immunity
Positive Regulation Of Regulated Secretory Pathway
Melanosome Organization
Pigment Granule Organization
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Natural Killer Cell Mediated Immunity
Regulation Of Defense Response To Virus By Virus
Positive Regulation Of Natural Killer Cell Activation
Regulation Of Regulated Secretory Pathway
Lysosomal Transport
Cellular Pigmentation
Positive Regulation Of Exocytosis
Developmental Pigmentation
Transport
Vacuolar Transport
Regulation Of Defense Response To Virus
Post-Golgi Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Positive Regulation Of Cell Killing
Regulation Of Leukocyte Mediated Cytotoxicity
Pigmentation
Regulation Of Exocytosis
Positive Regulation Of Innate Immune Response
Endosomal Transport
Vesicle Organization
Positive Regulation Of Protein Catabolic Process
Antigen Processing And Presentation Of Peptide Antigen
Regulation Of Innate Immune Response
Post-Golgi Vesicle-mediated Transport
Vesicle-mediated Transport
Membrane Organization
Golgi Vesicle Transport
Protein Transport
Establishment Of Protein Localization
Regulation Of Defense Response To Virus By Virus
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Protein Localization
Intracellular Transport
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Establishment Of Localization In Cell
Endocytosis
Cellular Localization
Regulation Of Defense Response To Virus
Transport
Establishment Of Vesicle Localization
Intracellular Protein Transport
Vesicle Localization
Cellular Protein Localization
Antigen Processing And Presentation Of Peptide Antigen
Antigen Processing And Presentation
Establishment Of Organelle Localization
Organelle Localization
Vesicle Targeting
Vesicle Organization
Viral Process
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Regulation Of Actin Nucleation
Vesicle Targeting, To, From Or Within Golgi
Regulation Of Synaptic Plasticity
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of Immune System Process
Regulation Of Endocytosis
Synaptic Vesicle Recycling
Receptor Internalization
Endosomal Transport
Negative Regulation Of Kit Signaling Pathway
Regulation Of Neuronal Synaptic Plasticity
Immune System Process
Vesicle Targeting, Trans-Golgi To Endosome
Synaptic Vesicle Membrane Organization
Regulation Of Synaptic Transmission
Membrane Budding
Receptor Metabolic Process
Receptor Internalization Involved In Canonical Wnt Signaling Pathway
Negative Regulation Of Hyaluronan Biosynthetic Process
Regulation Of Endosome Size
Regulation Of Opioid Receptor Signaling Pathway
Tagcloud
?
aberrantly
aberration
brcc3
cpxcr1
cxorf45
ddx53
dmd
fam9a
fhl1
gabre
gjb1
hdac8
hypermethylated
hypomethylated
hypomethylation
hysterectomy
irreversible
leiomyoma
leiomyomas
myometrium
nxf5
paired
pcdh11x
ream
taf1
tag
uterine
vbp1
xist
Tagcloud (Difference)
?
aberrantly
aberration
brcc3
cpxcr1
cxorf45
ddx53
dmd
fam9a
fhl1
gabre
gjb1
hdac8
hypermethylated
hypomethylated
hypomethylation
hysterectomy
irreversible
leiomyoma
leiomyomas
myometrium
nxf5
paired
pcdh11x
ream
taf1
tag
uterine
vbp1
xist
Tagcloud (Intersection)
?