AP1G1 and CLINT1

Number of citations of the paper that reports this interaction (PMID 12429846)
33

Data Source:
HPRD (in vitro)

		AP1G1	CLINT1
Gene Name		adaptor-related protein complex 1, gamma 1 subunit	clathrin interactor 1
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-type Membrane Coat Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome	Nucleoplasm Golgi Apparatus Cytosol Membrane Clathrin-coated Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Transporter Activity Protein Binding Protein Transporter Activity Rab GTPase Binding Kinesin Binding GTP-dependent Protein Binding	Protein Binding Lipid Binding Clathrin Binding
	Biological Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Membrane Organization Golgi To Lysosome Transport	Post-Golgi Vesicle-mediated Transport Endocytosis Clathrin Coat Assembly Membrane Organization
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 CLINT1 CLTC DNER KIF13A MAP1A RAB5A RABEP1 RABGEF1 SPTB SYNRG SYP UBL7 ZNF512B	12 interactors: AP1G1 AP2A1 AP2B1 CALM1 CLTC DNM1 EPS15 GGA1 GGA2 GGA3 JUN YWHAG
Entrez ID		164	9685
HPRD ID		04637	06273
Ensembl ID		ENSG00000166747	ENSG00000113282
Uniprot IDs		O43747 Q8IY97	Q14677
PDB IDs		1IU1	1XGW 2QY7 2V8S
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Membrane Organization Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Regulation Of Defense Response To Virus By Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Protein Localization Intracellular Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Establishment Of Localization In Cell Endocytosis Cellular Localization Regulation Of Defense Response To Virus Transport Establishment Of Vesicle Localization Intracellular Protein Transport Vesicle Localization Cellular Protein Localization Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Establishment Of Organelle Localization Organelle Localization Vesicle Targeting Vesicle Organization Viral Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Nucleation Vesicle Targeting, To, From Or Within Golgi Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Immune System Process Regulation Of Endocytosis Synaptic Vesicle Recycling Receptor Internalization Endosomal Transport Negative Regulation Of Kit Signaling Pathway Regulation Of Neuronal Synaptic Plasticity Immune System Process Vesicle Targeting, Trans-Golgi To Endosome Synaptic Vesicle Membrane Organization Regulation Of Synaptic Transmission Membrane Budding Receptor Metabolic Process Receptor Internalization Involved In Canonical Wnt Signaling Pathway Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Endosome Size Regulation Of Opioid Receptor Signaling Pathway	Establishment Of Localization In Cell Protein Transport Intracellular Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Protein Localization Cellular Protein Localization Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Negative Regulation Of Hyaluronan Biosynthetic Process Clathrin-mediated Endocytosis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Antigen Processing And Presentation Of Peptide Antigen Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Golgi Vesicle Transport Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Antigen Processing And Presentation Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ephrin Receptor Signaling Pathway Receptor-mediated Endocytosis Golgi To Endosome Transport Membrane Organization Regulation Of Protein Autophosphorylation Response To External Stimulus Endosomal Transport Axon Development Cellular Response To Growth Factor Stimulus Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Neurotrophin Signaling Pathway Receptor Internalization Regulation Of Immune System Process Cytoplasmic Transport Organelle Organization Immune System Process Nervous System Development Negative Regulation Of Protein Phosphorylation Cell Differentiation
Tagcloud ?			02mum 13mum 29ml aps consolidated cyp1a2 cyp2b6 cyp2c19 cyp2c8 cyp3a4 cyp450 dpa formations hlms invitro1 isozyme ketoconazole khellactone km1 m4 m5 m6 menten metabolisms michaelis naphthoflavone praeruptorin pyranocoumarins uhplc
Tagcloud (Difference) ?			02mum 13mum 29ml aps consolidated cyp1a2 cyp2b6 cyp2c19 cyp2c8 cyp3a4 cyp450 dpa formations hlms invitro1 isozyme ketoconazole khellactone km1 m4 m5 m6 menten metabolisms michaelis naphthoflavone praeruptorin pyranocoumarins uhplc
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