AP1G1 and ARF1

Number of citations of the paper that reports this interaction (PMID 11926829)
12

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		AP1G1	ARF1
Gene Name		adaptor-related protein complex 1, gamma 1 subunit	ADP-ribosylation factor 1
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-type Membrane Coat Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome	Golgi Membrane Cytosol Plasma Membrane Focal Adhesion Postsynaptic Density Sarcomere Neuron Projection Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Transporter Activity Protein Binding Protein Transporter Activity Rab GTPase Binding Kinesin Binding GTP-dependent Protein Binding	GTPase Activity Receptor Signaling Protein Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Membrane Organization Golgi To Lysosome Transport	Regulation Of Receptor Internalization Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Cellular Copper Ion Homeostasis Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Protein Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Arp2/3 Complex-mediated Actin Nucleation Small Molecule Metabolic Process COPI Coating Of Golgi Vesicle Regulation Of Defense Response To Virus By Virus Long Term Synaptic Depression Membrane Organization Dendritic Spine Organization
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System	Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Golgi Associated Vesicle Biogenesis Host Interactions of HIV factors The role of Nef in HIV-1 replication and disease pathogenesis Clathrin derived vesicle budding Lysosome Vesicle Biogenesis Golgi to ER Retrograde Transport MHC class II antigen presentation COPI Mediated Transport Phospholipid metabolism trans-Golgi Network Vesicle Budding Nef Mediated CD4 Down-regulation Adaptive Immune System PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 CLINT1 CLTC DNER KIF13A MAP1A RAB5A RABEP1 RABGEF1 SPTB SYNRG SYP UBL7 ZNF512B	40 interactors: AP1B1 AP1G1 AP3B1 AP3D1 AP3S2 AP4E1 AP4M1 ARFGAP1 ARFIP1 ARFIP2 ARHGAP21 ASAP1 ASAP2 CHRM3 COPB1 COPE COPG1 CYTH1 CYTH2 EEF1G GGA1 GGA2 GGA3 GOSR2 INSR KDELR1 MDM4 NOA1 NPM1 PICK1 PIP5K1A PLD1 PLD2 PLEKHA8 PLIN2 RALA TMED10 TMED2 TMEM106A WBP11
Entrez ID		164	375
HPRD ID		04637	00054
Ensembl ID		ENSG00000166747	ENSG00000143761
Uniprot IDs		O43747 Q8IY97	P84077
PDB IDs		1IU1	1HUR 1RE0 1U81 3O47 4HMY
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Membrane Organization Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Regulation Of Defense Response To Virus By Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Protein Localization Intracellular Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Establishment Of Localization In Cell Endocytosis Cellular Localization Regulation Of Defense Response To Virus Transport Establishment Of Vesicle Localization Intracellular Protein Transport Vesicle Localization Cellular Protein Localization Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Establishment Of Organelle Localization Organelle Localization Vesicle Targeting Vesicle Organization Viral Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Nucleation Vesicle Targeting, To, From Or Within Golgi Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Immune System Process Regulation Of Endocytosis Synaptic Vesicle Recycling Receptor Internalization Endosomal Transport Negative Regulation Of Kit Signaling Pathway Regulation Of Neuronal Synaptic Plasticity Immune System Process Vesicle Targeting, Trans-Golgi To Endosome Synaptic Vesicle Membrane Organization Regulation Of Synaptic Transmission Membrane Budding Receptor Metabolic Process Receptor Internalization Involved In Canonical Wnt Signaling Pathway Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Endosome Size Regulation Of Opioid Receptor Signaling Pathway	Intracellular Protein Transport Intracellular Transport Establishment Of Localization In Cell Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Cellular Protein Localization Protein Localization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Golgi Vesicle Transport Localization Within Membrane Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Transport Establishment Of Organelle Localization Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Organelle Localization Vesicle Targeting Membrane Organization Membrane Budding Organelle Organization Regulation Of ARF Protein Signal Transduction Cytoplasmic Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity Synaptic Vesicle Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Establishment Of Golgi Localization Golgi To Vacuole Transport Regulation Of Ras Protein Signal Transduction Endosome To Melanosome Transport Cargo Loading Into Vesicle Pigment Granule Maturation Axon Cargo Transport Intra-Golgi Vesicle-mediated Transport Cellular Pigment Accumulation Cellular Pigmentation
Tagcloud ?			adp bulk close coated coatomer consumed contact copi dynamics endoplasmic exchange explored fission golgi governed gtpase interconnected maintain maintenance mitochondria mitochondrial powerhouse presumably produce proximity reticulum ribosylation thought vesicles
Tagcloud (Difference) ?			adp bulk close coated coatomer consumed contact copi dynamics endoplasmic exchange explored fission golgi governed gtpase interconnected maintain maintenance mitochondria mitochondrial powerhouse presumably produce proximity reticulum ribosylation thought vesicles
Tagcloud (Intersection) ?