AP1G1 and SYNRG

Number of citations: 0 (PubMedID 10814529)
Data Source: HPRD (in vivo, two hybrid, in vitro)

		AP1G1	SYNRG
Name		adaptor related protein complex 1 subunit gamma 1	synergin gamma
Structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Clathrin-coated Pit Membrane Membrane Coat AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Synapse Perinuclear Region Of Cytoplasm Recycling Endosome Intracellular Vesicle Presynapse	Cytoplasm Golgi Apparatus Membrane AP-1 Adaptor Complex Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Collagen Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity	Protein Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Protein Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Synaptic Vesicle Endocytosis Platelet Dense Granule Organization Golgi To Lysosome Transport Basolateral Protein Secretion Melanosome Assembly	Intracellular Protein Transport Endocytosis Protein Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	None
GWAS		General cognitive ability ( 29844566 ) HDL cholesterol levels ( 32203549 ) Post bronchodilator FEV1 ( 26634245 ) Refractive error ( 32231278 ) Superior temporal sulcus banks volume ( 31530798 )	Lymphocyte count ( 32888494 ) Ovarian cancer ( 23535730 ) Response to angiotensin II receptor blocker therapy ( 22566498 )
Novel Interactors		1 novel interactors: UPF1	1 novel interactors: ARL6
Interacting Genes		30 interacting genes: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 GGA1 GGA2 GGA3 HEATR5B KIF13A MAP1A PLK2 PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 ZNF512B	8 interacting genes: AP1G1 AP1G2 APPBP2 CCDC91 GGA1 GGA2 GGA3 SCAMP1
Entrez ID		164	11276
HPRD ID		04637	06291
Ensembl ID		ENSG00000166747	ENSG00000275066
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	Q9UMZ2
PDB IDs		1IU1	2MX7
GO Terms Enriched among Interactors		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Clathrin-coated Vesicle AP-1 Adaptor Complex Intracellular Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Golgi Apparatus Early Endosome Post-Golgi Vesicle-mediated Transport Trans-Golgi Network Membrane Endocytosis Endosomal Transport Golgi To Plasma Membrane Transport Cytosolic Transport Vesicle-mediated Transport To The Plasma Membrane Golgi To Plasma Membrane Protein Transport Import Into Cell Cytoplasmic Vesicle Golgi Vesicle Transport Trans-Golgi Network Establishment Of Protein Localization To Plasma Membrane Basolateral Protein Secretion Clathrin-coated Pit Clathrin Binding Endosome Melanosome Organization Cytoplasmic Vesicle Membrane Pigment Granule Organization Retrograde Transport, Endosome To Golgi Cytosol Early Endosome Membrane Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Localization Within Membrane Melanosome Assembly Clathrin Adaptor Activity Clathrin Coat Assembly Platelet Dense Granule Organization Receptor-mediated Endocytosis Protein Localization To Membrane Vesicle Organization Membrane Coat Protein Localization To Cell Surface Protein Localization To Plasma Membrane Ubiquitin Binding Phosphatidylinositol Binding	Post-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Trans-Golgi Network Establishment Of Localization In Cell Intracellular Protein Transport Intracellular Protein Localization Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization To Plasma Membrane Cellular Localization Golgi To Vacuole Transport Membrane Coat Protein Localization To Cell Surface Golgi Apparatus Golgi To Plasma Membrane Protein Transport Vacuolar Transport Cytoplasmic Vesicle Membrane Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Golgi To Plasma Membrane Transport Clathrin-coated Vesicle Small GTPase Binding Endosome Membrane Protein Localization To Membrane Golgi To Lysosome Transport AP-1 Adaptor Complex Ubiquitin Binding Endosome Phosphatidylinositol Binding Lysosomal Transport Cytosolic Transport Clathrin Adaptor Activity Vesicle-mediated Transport To The Plasma Membrane Intracellular Vesicle Localization Within Membrane Early Endosome Membrane Membrane Protein Localization To Cilium Early Endosome Synaptic Vesicle Budding From Endosome Recycling Endosome Membrane Trans-Golgi Network Membrane Protein Transport From Ciliary Membrane To Plasma Membrane Recycling Endosome Basolateral Protein Secretion Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Lysosomal Protein Catabolic Process