AP1G1 and AFTPH

Number of citations of the paper that reports this interaction (PubMedID 14665628)
0

Data Source:
HPRD (two hybrid)

		AP1G1	AFTPH
Description		adaptor related protein complex 1 subunit gamma 1	aftiphilin
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Clathrin-coated Pit Membrane Membrane Coat AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Synapse Perinuclear Region Of Cytoplasm Recycling Endosome Intracellular Vesicle Presynapse	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Collagen Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity	Protein Binding Clathrin Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Protein Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Synaptic Vesicle Endocytosis Platelet Dense Granule Organization Golgi To Lysosome Transport Basolateral Protein Secretion Melanosome Assembly	Protein Transport Intracellular Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Delirium ( 29631748) Lung adenocarcinoma ( 31326317) Metabolite levels ( 23823483)
Interacting Genes		30 interacting genes: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 GGA1 GGA2 GGA3 HEATR5B KIF13A MAP1A PLK2 PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 ZNF512B	11 interacting genes: AP1G1 AP1G2 CLTC GGA1 GGA2 GGA3 LIG4 MAP1LC3B PEX14 STAT5B UBE3A
Entrez ID		164	54812
HPRD ID		04637	10635
Ensembl ID		ENSG00000166747	ENSG00000119844
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	A0A8Q3SI61 A0A8Q3SIA4 A0A8Q3WKU6 A0A8Q3WM48 Q53GW0 Q6ULP2
PDB IDs		1IU1
Enriched GO Terms of Interacting Partners?		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Clathrin-coated Vesicle AP-1 Adaptor Complex Intracellular Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Golgi Apparatus Early Endosome Post-Golgi Vesicle-mediated Transport Trans-Golgi Network Membrane Endocytosis Endosomal Transport Golgi To Plasma Membrane Transport Cytosolic Transport Vesicle-mediated Transport To The Plasma Membrane Golgi To Plasma Membrane Protein Transport Import Into Cell Cytoplasmic Vesicle Golgi Vesicle Transport Trans-Golgi Network Establishment Of Protein Localization To Plasma Membrane Basolateral Protein Secretion Clathrin-coated Pit Clathrin Binding Endosome Melanosome Organization Cytoplasmic Vesicle Membrane Pigment Granule Organization Retrograde Transport, Endosome To Golgi Cytosol Early Endosome Membrane Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Localization Within Membrane Melanosome Assembly Clathrin Adaptor Activity Clathrin Coat Assembly Platelet Dense Granule Organization Receptor-mediated Endocytosis Protein Localization To Membrane Vesicle Organization Membrane Coat Protein Localization To Cell Surface Protein Localization To Plasma Membrane Ubiquitin Binding Phosphatidylinositol Binding	Post-Golgi Vesicle-mediated Transport Intracellular Protein Transport Trans-Golgi Network Golgi Vesicle Transport Protein Localization To Cell Surface Protein Transport Golgi To Plasma Membrane Protein Transport Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Cellular Localization Establishment Of Localization In Cell Clathrin-coated Vesicle Small GTPase Binding Endosome Membrane AP-1 Adaptor Complex Intracellular Protein Localization Ubiquitin Binding Phosphatidylinositol Binding Clathrin Adaptor Activity Endosome Golgi To Vacuole Transport Cytosolic Transport Intracellular Vesicle Vesicle-mediated Transport To The Plasma Membrane Protein-containing Complex Disassembly Vacuolar Transport Membrane Coat Cytoplasmic Vesicle Membrane Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Protein Localization To Plasma Membrane Positive Regulation Of Natural Killer Cell Mediated Immunity Early Endosome Membrane Establishment Of Protein Localization To Membrane T Cell Differentiation In Thymus Protein Localization To Cell Periphery Regulation Of Natural Killer Cell Mediated Cytotoxicity Endosomal Transport Regulation Of Natural Killer Cell Mediated Immunity Establishment Of Integrated Proviral Latency Peroxisome Transport Along Microtubule Sperm Entry Positive Regulation Of Golgi Lumen Acidification Positive Regulation Of Leukocyte Mediated Cytotoxicity Golgi Apparatus Positive Regulation Of Cell Killing Protein Localization To Membrane Clathrin-coated Pit
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