AP1S2 and MAB21L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AP1S2	MAB21L2
Description		adaptor related protein complex 1 subunit sigma 2	mab-21 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Early Endosome Golgi Apparatus Cytosol Clathrin-coated Pit Membrane Membrane Coat AP-type Membrane Coat Adaptor Complex AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm
	Molecular Function	Protein Binding Clathrin Adaptor Activity	Protein Binding
	Biological Process	Intracellular Protein Transport Protein Transport Vesicle-mediated Transport Platelet Dense Granule Organization Melanosome Assembly	Eye Development Nervous System Development Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Embryonic Body Morphogenesis Camera-type Eye Development
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Lung function (FEV1/FVC) ( 26635082)
Interacting Genes		5 interacting genes: AP1G1 AP1G2 GGA3 MAB21L2 TNS2	15 interacting genes: ABI1 AP1S2 APP ARID5A CCDC102B CEP70 GOLGA2 GOLGA6L9 KRT31 KRT34 KRT40 MEOX2 PNMA1 SRPK2 TFIP11
Entrez ID		8905	10586
HPRD ID		04636	05075
Ensembl ID		ENSG00000182287	ENSG00000181541
Uniprot IDs		A0A5F9ZHW1 A0A5F9ZI43 A6NH01 H7BZG6 P56377 Q549M9	Q9Y586
PDB IDs
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Clathrin Adaptor Activity Intracellular Vesicle Golgi To Vacuole Transport Vacuolar Transport AP-1 Adaptor Complex Membrane Coat Golgi Vesicle Transport Intracellular Protein Transport Lysosomal Transport Synaptic Vesicle Budding From Endosome Recycling Endosome Cytoplasmic Vesicle Membrane Basolateral Protein Secretion Positive Regulation Of Natural Killer Cell Degranulation Trans-Golgi Network Positive Regulation Of Lysosomal Protein Catabolic Process Small GTPase Binding Vesicle-mediated Transport Protein Transport Endosome To Melanosome Transport Intracellular Transport Endosome Membrane Body Morphogenesis Embryonic Body Morphogenesis Positive Regulation Of Protein Catabolic Process In The Vacuole Golgi To Lysosome Transport Regulation Of Lysosomal Protein Catabolic Process Early Endosome Establishment Of Protein Localization Golgi Apparatus Protein Transporter Activity Golgi-associated Vesicle Melanosome Assembly GTP-dependent Protein Binding Cellular Localization Establishment Of Localization In Cell Peptidyl-tyrosine Dephosphorylation Platelet Dense Granule Organization Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Protein Targeting To Lysosome Protein Localization To Cell Surface Response To Muscle Activity Intracellular Protein Localization Vesicle Budding From Membrane Positive Regulation Of Natural Killer Cell Mediated Immunity Clathrin-coated Vesicle Membrane Golgi To Plasma Membrane Protein Transport	Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Cytoskeleton Protein Serine/threonine Kinase Binding Intermediate Filament Structural Molecule Activity Organelle Organization
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