AP1G1 and DNER

Number of citations of the paper that reports this interaction (PMID 11950833)
8

Data Source:
HPRD (in vivo)

		AP1G1	DNER
Gene Name		adaptor-related protein complex 1, gamma 1 subunit	delta/notch-like EGF repeat containing
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-type Membrane Coat Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome	Early Endosome Plasma Membrane Integral Component Of Membrane Dendrite Neuronal Cell Body
	Molecular Function	Transporter Activity Protein Binding Protein Transporter Activity Rab GTPase Binding Kinesin Binding GTP-dependent Protein Binding	Transmembrane Signaling Receptor Activity Notch Binding Calcium Ion Binding Protein Binding Clathrin Binding
	Biological Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Membrane Organization Golgi To Lysosome Transport	Neuron Migration Endocytosis Notch Signaling Pathway Notch Receptor Processing Synapse Assembly Central Nervous System Development Glial Cell Differentiation Skeletal Muscle Fiber Development
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System	Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS			Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		20 interactors: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 CLINT1 CLTC DNER KIF13A MAP1A RAB5A RABEP1 RABGEF1 SPTB SYNRG SYP UBL7 ZNF512B	1 interactors: AP1G1
Entrez ID		164	92737
HPRD ID		04637	09531
Ensembl ID		ENSG00000166747	ENSG00000187957
Uniprot IDs		O43747 Q8IY97	Q8NFT8
PDB IDs		1IU1
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Membrane Organization Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Regulation Of Defense Response To Virus By Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Protein Localization Intracellular Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Establishment Of Localization In Cell Endocytosis Cellular Localization Regulation Of Defense Response To Virus Transport Establishment Of Vesicle Localization Intracellular Protein Transport Vesicle Localization Cellular Protein Localization Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Establishment Of Organelle Localization Organelle Localization Vesicle Targeting Vesicle Organization Viral Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Nucleation Vesicle Targeting, To, From Or Within Golgi Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Immune System Process Regulation Of Endocytosis Synaptic Vesicle Recycling Receptor Internalization Endosomal Transport Negative Regulation Of Kit Signaling Pathway Regulation Of Neuronal Synaptic Plasticity Immune System Process Vesicle Targeting, Trans-Golgi To Endosome Synaptic Vesicle Membrane Organization Regulation Of Synaptic Transmission Membrane Budding Receptor Metabolic Process Receptor Internalization Involved In Canonical Wnt Signaling Pathway Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Endosome Size Regulation Of Opioid Receptor Signaling Pathway	Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport Golgi To Vacuole Transport Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Regulated Secretory Pathway Melanosome Organization Pigment Granule Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Defense Response To Virus By Virus Positive Regulation Of Natural Killer Cell Activation Regulation Of Regulated Secretory Pathway Lysosomal Transport Cellular Pigmentation Positive Regulation Of Exocytosis Developmental Pigmentation Vacuolar Transport Regulation Of Defense Response To Virus Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Pigmentation Regulation Of Exocytosis Positive Regulation Of Innate Immune Response Endosomal Transport Vesicle Organization Antigen Processing And Presentation Of Peptide Antigen Regulation Of Innate Immune Response Golgi Vesicle Transport Antigen Processing And Presentation Positive Regulation Of Cell Activation Positive Regulation Of Secretion Regulation Of Vesicle-mediated Transport Regulation Of Lymphocyte Activation Regulation Of Cell Activation Viral Process Positive Regulation Of Immune Response Regulation Of Secretion Cytoplasmic Transport Positive Regulation Of Transport
Tagcloud ?			ampar amphiphysin autoantibody caspr2 cna crmp5 csna cv2 delineated fundamentally gabaar gababr gad65 glyr hu iglons immunomodulator isa lgi1 mglur1 mglur5 oncological paraneoplastic pns ri sox vgcc yo zic4
Tagcloud (Difference) ?			ampar amphiphysin autoantibody caspr2 cna crmp5 csna cv2 delineated fundamentally gabaar gababr gad65 glyr hu iglons immunomodulator isa lgi1 mglur1 mglur5 oncological paraneoplastic pns ri sox vgcc yo zic4
Tagcloud (Intersection) ?