RUNX1 and CDK6

  • Number of citations of the paper that reports this interaction (PMID 17431401)
  • 18
  • Data Source:
  • HPRD (in vivo)

RUNX1

CDK6

Gene Name runt-related transcription factor 1 cyclin-dependent kinase 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 46 interactors: AES AR CBFA2T2 CBFA2T3 CBFB CCND1 CCND2 CCND3 CDK1 CDK6 CEBPA CEBPB COPRS CTBP2 DNMT1 EFNA2 ELF2 ELF4 EP300 ETS1 FOS FOXP3 HDAC1 HDAC3 HIPK1 HIPK2 JUN KAT6A KAT6B MYOD1 NCOR1 NCOR2 PAX5 PRMT1 RBM14 SPEN STUB1 SUV39H1 TAZ TLE1 TLE2 UBE2L6 UXT VDR WWTR1 YAP1 92 interactors: ABI2 ANKRD12 AR ATF6B ATXN1 BCL11A CASC3 CBY1 CCND1 CCND3 CDC37 CDC6 CDK7 CDKN1A CDKN2A CDKN2B CDKN2C CDKN2D CLASRP CNOT7 CTNNB1 DAB1 DDIT3 DEDD2 EBF4 EIF4ENIF1 ELK1 EZH2 FOXM1 FOXO3 HIST1H1A HSF1 ISL1 KIF26B KLF10 LPIN1 MCM10 MCM2 MEF2D MLLT3 MSL3 MYC MZF1 N4BP1 NFATC3 NIPBL NUMA1 PCNA PML POGZ PPARGC1A PPHLN1 PPM1B PPP2CA PRX PSMA3 RB1 RBL1 RBL2 RBM23 RUNX1 SENP3 SIRT1 SLBP SNIP1 SORBS1 SOX10 SOX5 SRSF1 SRSF11 SRSF12 SRSF2 SRSF7 SSBP2 SYNPO2 TCEB3B TFDP1 TGFBR1 TJP2 TPX2 TRA2A TRA2B TRAK1 UHRF2 VGLL4 ZEB1 ZFP36 ZMYM3 ZNF101 ZNF174 ZNF335 ZSCAN1
Entrez ID 861 1021
HPRD ID 01043 04533
Ensembl ID ENSG00000159216 ENSG00000105810
Uniprot IDs Q01196 A4D1G0 Q00534
PDB IDs 1CMO 1CO1 1E50 1H9D 1LJM 1BI7 1BI8 1BLX 1G3N 1JOW 1XO2 2EUF 2F2C 3NUP 3NUX 4AUA 4EZ5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx2  runx3  syndromes  unmethylated 
a134c  abp  allelic  ankyrin  balb  cdkn2a  cdkn2b  cdkn2c  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p15  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Difference) ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx2  runx3  syndromes  unmethylated 
a134c  abp  allelic  ankyrin  balb  cdkn2a  cdkn2b  cdkn2c  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p15  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Intersection) ?