RUNX1 and RBM14

Number of citations of the paper that reports this interaction (PMID 19585539)
5

Data Source:
BioGRID (pull down)

		RUNX1	RBM14
Gene Name		runt-related transcription factor 1	RNA binding motif protein 14
Image
Gene Ontology Annotations	Cellular Component	Basement Membrane Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle	Nucleoplasm Transcription Factor Complex Nucleolus Mediator Complex Ribonucleoprotein Complex
	Molecular Function	Regulatory Region DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Calcium Ion Binding Protein Binding ATP Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity Repressing Transcription Factor Binding	Nucleotide Binding RNA Polymerase II Transcription Cofactor Activity RNA Binding Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Protein Binding, Bridging Poly(A) RNA Binding
	Biological Process	Skeletal System Development In Utero Embryonic Development Liver Development Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Central Nervous System Development Regulation Of Signal Transduction Hemopoiesis Myeloid Cell Differentiation Negative Regulation Of Granulocyte Differentiation Positive Regulation Of Granulocyte Differentiation Hair Follicle Morphogenesis Embryonic Hemopoiesis Positive Regulation Of Angiogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Behavioral Response To Pain Peripheral Nervous System Neuron Development Definitive Hemopoiesis Regulation Of Hair Follicle Cell Proliferation Hematopoietic Stem Cell Proliferation Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Progesterone Secretion	DNA Replication DNA Repair DNA Recombination Transcription From RNA Polymerase II Promoter Response To Hormone Histone Deacetylation Intracellular Estrogen Receptor Signaling Pathway Glucocorticoid Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Esophageal cancer ( 21642993) Immune response to smallpox vaccine (IL-6) ( 22542470) Phospholipid levels (plasma) ( 21829377) Preeclampsia ( 23551011)	Bipolar disorder ( 21926972)
Protein-Protein Interactions		46 interactors: AES AR CBFA2T2 CBFA2T3 CBFB CCND1 CCND2 CCND3 CDK1 CDK6 CEBPA CEBPB COPRS CTBP2 DNMT1 EFNA2 ELF2 ELF4 EP300 ETS1 FOS FOXP3 HDAC1 HDAC3 HIPK1 HIPK2 JUN KAT6A KAT6B MYOD1 NCOR1 NCOR2 PAX5 PRMT1 RBM14 SPEN STUB1 SUV39H1 TAZ TLE1 TLE2 UBE2L6 UXT VDR WWTR1 YAP1	11 interactors: EP300 NCOA6 NR3C1 PARP1 QKI RUNX1 RUNX2 SS18 SYT1 TARBP2 XRCC5
Entrez ID		861	10432
HPRD ID		01043	11485
Ensembl ID		ENSG00000159216
Uniprot IDs		Q01196	Q96PK6
PDB IDs		1CMO 1CO1 1E50 1H9D 1LJM	2DNP
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Gene Expression RNA Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Developmental Process System Development Regulation Of Cellular Process Cell Differentiation Multicellular Organismal Development Anatomical Structure Development Notch Signaling Pathway Chromatin Organization Cellular Metabolic Process Chromatin Modification Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Cell Differentiation Response To Organic Substance	RNA Metabolic Process Positive Regulation Of Gene Expression Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated Heterocycle Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance DNA-templated Transcription, Initiation Glucocorticoid Receptor Signaling Pathway Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Hemopoiesis Regulation Of Transcription, DNA-templated Immune System Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Biosynthetic Process Anatomical Structure Development Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Developmental Process Regulation Of Metabolic Process System Development Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Immune System Process Myeloid Cell Differentiation Negative Regulation Of Gene Expression Response To Stimulus Multicellular Organismal Development Cell Differentiation Cellular Response To Stimulus Chordate Embryonic Development Anatomical Structure Morphogenesis Stem Cell Differentiation
Tagcloud ?		1q22 aml correlative cytogenetic decitabine demethylating elucidate epigenetics frequent haematological hypermethylation inactivation inv leukaemia leukaemias lymphocytic malignancies methylated mostly myelodysplatic p13 promoters re relapse runx2 runx3 syndromes unmethylated	aggregating conjugation detergent dialkylated eif4a1 g3bp glycine granular hek hnrnps identities immunocytochemistry insoluble isotope nono oligomerization pabpc1 paraspeckle proteinopathies psf ptm quantitate rgg rrm s6 silac tdp tls ubiquitination
Tagcloud (Difference) ?		1q22 aml correlative cytogenetic decitabine demethylating elucidate epigenetics frequent haematological hypermethylation inactivation inv leukaemia leukaemias lymphocytic malignancies methylated mostly myelodysplatic p13 promoters re relapse runx2 runx3 syndromes unmethylated	aggregating conjugation detergent dialkylated eif4a1 g3bp glycine granular hek hnrnps identities immunocytochemistry insoluble isotope nono oligomerization pabpc1 paraspeckle proteinopathies psf ptm quantitate rgg rrm s6 silac tdp tls ubiquitination
Tagcloud (Intersection) ?