RUNX1 and NCOR2

  • Number of citations of the paper that reports this interaction (PMID 17560331)
  • 27
  • Data Source:
  • BioGRID (x-ray crystallography)
  • HPRD (two hybrid)

RUNX1

NCOR2

Gene Name runt-related transcription factor 1 nuclear receptor corepressor 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065)
  • Cognitive performance ( 19734545)
Protein-Protein Interactions 46 interactors: AES AR CBFA2T2 CBFA2T3 CBFB CCND1 CCND2 CCND3 CDK1 CDK6 CEBPA CEBPB COPRS CTBP2 DNMT1 EFNA2 ELF2 ELF4 EP300 ETS1 FOS FOXP3 HDAC1 HDAC3 HIPK1 HIPK2 JUN KAT6A KAT6B MYOD1 NCOR1 NCOR2 PAX5 PRMT1 RBM14 SPEN STUB1 SUV39H1 TAZ TLE1 TLE2 UBE2L6 UXT VDR WWTR1 YAP1 84 interactors: AHR AKT1 AP2M1 AR ARNT ATXN1 ATXN1L BCL6 C1D CBFA2T2 CEBPB CEP63 CHUK CIR1 CNOT2 DDX20 E2F1 ESR1 ESR2 FOS FOXP1 HDAC1 HDAC10 HDAC3 HDAC4 HDAC5 HDAC7 HIST1H4A HNF4A INPP5K IRF5 JUN MYBL2 MYOD1 NCOA3 NCOA6 NCOR1 NFE2L2 NFKB1 NFKBIA NFKBIB NFKBIE NR1D1 NR1H2 NR1H4 NR1I2 NR2F1 NR2F2 NR3C1 NR4A1 PML POU2F1 PPARA PPARD PPARG RANBP9 RARA RARB RARG RBPJ RELA RUNX1 RUNX1T1 RXRA RXRG SAP30 SIN3A SKIL SNW1 SP1 SPEN SRF STAT5A STAT5B SUMO1 TBL1X THRA THRB TNIK TNIP2 UBE2I VDR YWHAE ZBTB16
Entrez ID 861 9612
HPRD ID 01043 02910
Ensembl ID ENSG00000159216 ENSG00000196498
Uniprot IDs Q01196 C9J0Q5 C9JE98 C9JFD3 Q9Y618
PDB IDs 1CMO 1CO1 1E50 1H9D 1LJM 1KKQ 1R2B 1XC5 2GPV 2L5G 2LTP 2ODD 3R29 3R2A 4A69
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx2  runx3  syndromes  unmethylated 
amico  atm  dissect  entered  erg  formalin  fusions  hiseq  illumina  map2k5  maximise  mek5  men1  nbpf10  needle  ngs  opening  pik3cb  qiagen  read  routinely  screen  sections  spop  technologies  templates  tmprrs2  unstained  yielded 
Tagcloud (Difference) ?
1q22  aml  correlative  cytogenetic  decitabine  demethylating  elucidate  epigenetics  frequent  haematological  hypermethylation  inactivation  inv  leukaemia  leukaemias  lymphocytic  malignancies  methylated  mostly  myelodysplatic  p13  promoters  re  relapse  runx2  runx3  syndromes  unmethylated 
amico  atm  dissect  entered  erg  formalin  fusions  hiseq  illumina  map2k5  maximise  mek5  men1  nbpf10  needle  ngs  opening  pik3cb  qiagen  read  routinely  screen  sections  spop  technologies  templates  tmprrs2  unstained  yielded 
Tagcloud (Intersection) ?