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KCNAB2 and SQSTM1
Number of citations of the paper that reports this interaction (PMID
12431995
)
13
Data Source:
HPRD
(two hybrid, in vitro)
KCNAB2
SQSTM1
Gene Name
potassium channel, voltage gated subfamily A regulatory beta subunit 2
sequestosome 1
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Microtubule
Plasma Membrane
Voltage-gated Potassium Channel Complex
Membrane
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Juxtaparanode Region Of Axon
Pinceau Fiber
Pre-autophagosomal Structure
Cytoplasmic MRNA Processing Body
Nucleoplasm
Cytoplasm
Lysosome
Late Endosome
Autophagic Vacuole
Endoplasmic Reticulum
Cytosol
Inclusion Body
Aggresome
PML Body
Cytoplasmic Vesicle
Extracellular Vesicular Exosome
Molecular Function
Aldo-keto Reductase (NADP) Activity
Voltage-gated Potassium Channel Activity
Potassium Channel Regulator Activity
Protein Serine/threonine Kinase Activity
Protein Kinase C Binding
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Receptor Tyrosine Kinase Binding
SH2 Domain Binding
Identical Protein Binding
Protein Homodimerization Activity
Ubiquitin Binding
K63-linked Polyubiquitin Binding
Biological Process
Hematopoietic Progenitor Cell Differentiation
Synaptic Transmission
Protein Heterooligomerization
Oxidation-reduction Process
NADPH Oxidation
Potassium Ion Transmembrane Transport
Regulation Of Potassium Ion Transmembrane Transport
Regulation Of Protein Localization To Cell Surface
Positive Regulation Of Protein Phosphorylation
Immune System Process
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Response To Stress
Protein Localization
Endosomal Transport
Macroautophagy
Positive Regulation Of Macroautophagy
Cell Differentiation
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Ras Protein Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Protein Heterooligomerization
Apoptotic Signaling Pathway
Pathways
Potassium Channels
Voltage gated Potassium channels
Signaling by Interleukins
Signalling by NGF
NF-kB is activated and signals survival
p75NTR recruits signalling complexes
Cell death signalling via NRAGE, NRIF and NADE
NRIF signals cell death from the nucleus
p75NTR signals via NF-kB
Cytokine Signaling in Immune system
Interleukin-1 signaling
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
ATXN1
CD4
KCNA2
NEDD4
NEDD4L
SLC39A1
SLC39A2
SQSTM1
74 interactors:
ATXN3
BCL2
BMPR1B
BPTF
CALM1
CAMK2A
CCNB1
CDC37
CDK1
CSNK2A1
DAZAP2
EEF1D
EGLN3
FKBP4
GABARAPL1
GABARAPL2
GABRR1
GABRR2
GEMIN4
GRB14
GRIA1
GRIA2
GRIA3
IRAK1
KCNAB2
KEAP1
LCK
LINC00341
MALT1
MAP1LC3A
MAP1LC3B
MAP2K5
MAP3K3
MAPK14
MBP
MEIS2
MLH1
NBR1
NCOR1
NR2F2
NTRK1
NTRK2
NTRK3
OPTN
PAWR
PIK3CA
PPHLN1
PRKCI
PRKCZ
RAD23A
RELN
RIPK1
RPL37
SMAD1
SMAD2
SMAD3
SMAD4
SMURF1
SNCA
STXBP1
TGFBR1
TKT
TOE1
TP53
TRAF6
TRIM55
TRIM63
TTN
UBA52
UBB
UBC
ULK1
ULK2
YWHAZ
Entrez ID
8514
8878
HPRD ID
03090
03319
Ensembl ID
ENSG00000069424
ENSG00000161011
Uniprot IDs
B2R776
Q13303
Q2YD85
Q13501
PDB IDs
1ZSX
1Q02
2JY7
2JY8
2K0B
2KNV
Enriched GO Terms of Interacting Partners
?
Regulation Of Membrane Potential
Negative Regulation Of Sodium Ion Transport
Zinc Ion Transmembrane Transport
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of Potassium Ion Transmembrane Transporter Activity
Zinc Ion Transport
Regulation Of Potassium Ion Transmembrane Transport
Protein Monoubiquitination
Metal Ion Transport
Transport
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Potassium Ion Transport
Regulation Of Sodium Ion Transport
Regulation Of Ion Transmembrane Transport
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Induction By Virus Of Host Cell-cell Fusion
Transmission Of Virus
Protein Palmitoleylation
Development Involved In Symbiotic Interaction
Action Potential
Cation Transport
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Ion Transport
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Interaction With Host
Ion Transmembrane Transport
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Viral Process
Proteolysis Involved In Cellular Protein Catabolic Process
Optic Nerve Structural Organization
Positive Regulation Of Caveolin-mediated Endocytosis
Cellular Protein Catabolic Process
Protein Catabolic Process
Regulation Of Signal Transduction
Regulation Of Ion Transport
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Protein Polyubiquitination
Regulation Of Signaling
Transmembrane Transport
Regulation Of Cellular Response To Growth Factor Stimulus
Ion Transport
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Caveolin-mediated Endocytosis
Progesterone Receptor Signaling Pathway
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Negative Regulation Of Sodium Ion Transmembrane Transport
Cell Communication
Response To Growth Factor
Cellular Response To Growth Factor Stimulus
Cellular Response To Stimulus
Response To Stimulus
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Phosphorylation
Response To Stress
Regulation Of Phosphorylation
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Signaling
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Protein Kinase Activity
Phosphorylation
Cellular Response To Organic Substance
Regulation Of Kinase Activity
Positive Regulation Of Protein Kinase Activity
Signal Transduction
Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Signal Transduction
Positive Regulation Of Transferase Activity
Positive Regulation Of Kinase Activity
Regulation Of Cell Death
Negative Regulation Of Cell Death
Response To Organic Substance
Regulation Of Signal Transduction
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Cellular Metabolic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Metabolic Process
Protein Phosphorylation
Activation Of Protein Kinase Activity
Membrane Organization
Neurotrophin TRK Receptor Signaling Pathway
Cellular Component Assembly
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Catalytic Activity
Cell Surface Receptor Signaling Pathway
Cellular Response To Stress
Tagcloud
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
warranted
wnt1
Tagcloud (Difference)
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
warranted
wnt1
Tagcloud (Intersection)
?