CHEK1 and TLK1

  • Number of citations of the paper that reports this interaction (PMID 12660173)
  • 37
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vivo, in vitro)

CHEK1

TLK1

Gene Name checkpoint kinase 1 tousled-like kinase 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 37 interactors: AATF AKT1 APP ATM ATR BLM BRCA1 CDC25A CDC25B CDC25C CHUK CLSPN CSNK2B CUL1 CUL4A DTL FANCE HSP90AA1 LATS2 MCPH1 MDM4 PIGM PRKDC RAD51 RB1 RELA SMAD4 TIMELESS TLK1 TOPBP1 TP53 UBB USP7 XIAP XPO1 XRCC6 YWHAG 13 interactors: ASF1A ASF1B AURKA CHEK1 HIST1H1A LUZP4 MBP NBN SNAP23 TLK2 TPM3 UBE3C YWHAE
Entrez ID 1111 9874
HPRD ID 04356 12232
Ensembl ID ENSG00000149554 ENSG00000198586
Uniprot IDs B4DT73 O14757 Q9UKI8
PDB IDs 1IA8 1NVQ 1NVR 1NVS 1ZLT 1ZYS 2AYP 2BR1 2BRB 2BRG 2BRH 2BRM 2BRN 2BRO 2C3J 2C3K 2C3L 2CGU 2CGV 2CGW 2CGX 2E9N 2E9O 2E9P 2E9U 2E9V 2GDO 2GHG 2HOG 2HXL 2HXQ 2HY0 2QHM 2QHN 2R0U 2WMQ 2WMR 2WMS 2WMT 2WMU 2WMV 2WMW 2WMX 2X8D 2X8E 2X8I 2XEY 2XEZ 2XF0 2YDI 2YDJ 2YDK 2YER 2YEX 2YM3 2YM4 2YM5 2YM6 2YM7 2YM8 2YWP 3F9N 3JVR 3JVS 3NLB 3OT3 3OT8 3PA3 3PA4 3PA5 3TKH 3TKI 3U9N 4FSM 4FSN 4FSQ 4FSR 4FST 4FSU 4FSW 4FSY 4FSZ 4FT0 4FT3 4FT5 4FT7 4FT9 4FTA 4FTC 4FTI 4FTJ 4FTK 4FTL 4FTM 4FTN 4FTO 4FTQ 4FTR 4FTT 4FTU 4GH2 4HYH 4HYI 4JIK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aggressive  atr  bcss  clinically  consequences  cytoplasmic  deregulated  doxycycline  knock  lymphovascular  mb  mcf10a  mcf7  mda  mitotic  personalized  phenotypes  pleomorphism  positivity  predictor  rational  restored  ser345  serine345  signalling  tumorigenic  univariate  ve 
asymmetric  belonging  cloned  coefficient  crystallization  crystals  cubic  diffracting  diffraction  evolutionarily  hetero  homo  homogeneity  i4122  localize  matthews  namely  oligomers  p213  purification  segregation  solvent  synchrotron  tetragonal  threonine  tlk2  tlks  tousled  yielded 
Tagcloud (Difference) ?
aggressive  atr  bcss  clinically  consequences  cytoplasmic  deregulated  doxycycline  knock  lymphovascular  mb  mcf10a  mcf7  mda  mitotic  personalized  phenotypes  pleomorphism  positivity  predictor  rational  restored  ser345  serine345  signalling  tumorigenic  univariate  ve 
asymmetric  belonging  cloned  coefficient  crystallization  crystals  cubic  diffracting  diffraction  evolutionarily  hetero  homo  homogeneity  i4122  localize  matthews  namely  oligomers  p213  purification  segregation  solvent  synchrotron  tetragonal  threonine  tlk2  tlks  tousled  yielded 
Tagcloud (Intersection) ?