MCM6 and SNRPB2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MCM6	SNRPB2
Gene Name		minichromosome maintenance complex component 6	small nuclear ribonucleoprotein polypeptide B
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MCM Complex	Nucleoplasm Spliceosomal Complex U2 SnRNP Nucleolus Catalytic Step 2 Spliceosome
	Molecular Function	Single-stranded DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding Identical Protein Binding	Nucleotide Binding Protein Binding SnRNA Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression
Pathways		Synthesis of DNA G2/M Checkpoints Activation of the pre-replicative complex DNA Replication Pre-Initiation M/G1 Transition Regulation of DNA replication Activation of the pre-replicative complex Orc1 removal from chromatin S Phase DNA strand elongation Cell Cycle, Mitotic Assembly of the pre-replicative complex Orc1 removal from chromatin G1/S Transition Activation of ATR in response to replication stress Cell Cycle Checkpoints Removal of licensing factors from origins Mitotic G1-G1/S phases Switching of origins to a post-replicative state Unwinding of DNA	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: ALS2CR11 CCNA1 CDC45 CDC7 CDKN2A CDT1 CRLS1 DBF4 FAM161A GMNN HDAC1 IL36RN ING5 MCM10 MCM2 MCM3 MCM4 MCM7 MCM8 MLLT3 NUDT2 ORC1 ORC2 ORC4 ORC6 PSMA1 RPA1 SCNM1 SMC1A SNRPB2 ZBTB9	16 interactors: CALM1 DHX9 GABPB1 GOLGA2 HMBOX1 HNRNPUL1 HOMEZ HTATSF1 MCM6 MTUS2 PNMA1 SMN2 SNRPA1 SUGP1 TRIM27 ZBTB14
Entrez ID		4175	6629
HPRD ID		03485	04628
Ensembl ID		ENSG00000076003	ENSG00000125870
Uniprot IDs		Q14566	P08579
PDB IDs		2KLQ 2LE8	1A9N
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle DNA Replication Mitotic Cell Cycle Process DNA-dependent DNA Replication DNA Replication Initiation Cell Cycle Cell Cycle Process DNA Metabolic Process DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle DNA Duplex Unwinding DNA Geometric Change DNA Unwinding Involved In DNA Replication Chromosome Organization Cellular Metabolic Process DNA Conformation Change Regulation Of Cell Cycle Double-strand Break Repair Via Break-induced Replication Regulation Of Cell Cycle Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To DNA Damage Stimulus Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of DNA Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Double-strand Break Repair Cellular Response To Stress Regulation Of Nuclear Cell Cycle DNA Replication DNA Replication Checkpoint Cellular Process Positive Regulation Of Cell Cycle Process Cell Cycle Checkpoint DNA Recombination Organelle Organization Negative Regulation Of Cell Cycle	RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Processing MRNA Metabolic Process RNA Processing Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA Duplex Unwinding DNA Geometric Change Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Ion Transport Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity CRD-mediated MRNA Stabilization Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Calcium Ion Import Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Nitrogen Compound Metabolic Process Interferon-gamma Secretion Regulation Of Calcium Ion Transport Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Immune Response Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Detection Of Calcium Ion Defense Response Negative Regulation Of Biosynthetic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity DNA Unwinding Involved In DNA Replication
Tagcloud ?		benign bronchial brushing brushings clinicopathologic considerable consisting cytology detecting icbp90 immunocytochemistry inpatients ki67 kiaa0317 kiaa1522 ligase lung mcm7 minichromosome nonsmall nsclc outpatients panel sclc specimens tp53 tp63 uhr1 uncharacterized	acetyltransferase aggregates als amyotrophic anacardic candidates carry cytoskeletal cytosolic degenerate detergent elucidating familial fatal generate hampered insoluble ipsc ipscs motor neurites neuron neurons pluripotent postmortem rescued spliceosomal tar zebrafish
Tagcloud (Difference) ?		benign bronchial brushing brushings clinicopathologic considerable consisting cytology detecting icbp90 immunocytochemistry inpatients ki67 kiaa0317 kiaa1522 ligase lung mcm7 minichromosome nonsmall nsclc outpatients panel sclc specimens tp53 tp63 uhr1 uncharacterized	acetyltransferase aggregates als amyotrophic anacardic candidates carry cytoskeletal cytosolic degenerate detergent elucidating familial fatal generate hampered insoluble ipsc ipscs motor neurites neuron neurons pluripotent postmortem rescued spliceosomal tar zebrafish
Tagcloud (Intersection) ?