IKZF1 and KIF9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF1	KIF9
Gene Name		IKAROS family zinc finger 1 (Ikaros)	kinesin family member 9
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Pericentric Heterochromatin Cytoplasm Protein Complex	Podosome Cytoplasm Kinesin Complex Microtubule Vesicle
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation Transcription, DNA-templated Cell Cycle Mesoderm Development Chromatin Modification B Cell Differentiation T Cell Differentiation Forebrain Development Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Thymus Development Peyer's Patch Development Positive Regulation Of NK T Cell Differentiation Retina Development In Camera-type Eye	Microtubule-based Movement Blood Coagulation Metabolic Process Extracellular Matrix Disassembly Regulation Of Podosome Assembly Organelle Disassembly
Pathways			Kinesins Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23512250 19684603 19684604) Crohn's disease ( 21102463) Hippocampal atrophy ( 19668339) IgG glycosylation ( 23382691) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 19838193)
Protein-Protein Interactions		75 interactors: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C19orf66 C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 CTBP2 DCX DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FRMD6 GLRX3 GMCL1P1 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MTA1 NEK6 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I WTAP ZMAT2 ZNF417 ZNF581	13 interactors: CARD9 EFHC2 IKZF1 JAKMIP2 KRTAP10-3 KRTAP10-9 LZTS2 PRMT6 ROPN1 SSX2IP TRIM27 TRIM37 ZBTB8A
Entrez ID		10320	64147
HPRD ID		04318	07444
Ensembl ID		ENSG00000185811	ENSG00000088727
Uniprot IDs		Q13422	A8K932 Q9HAQ2
PDB IDs			3NWN
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Organelle Organization Chromosome Organization Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA Repair Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Splicing	Organelle Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone H3-R2 Methylation Negative Regulation Of Interleukin-2 Secretion Chromatin Modification Histone H2A-K119 Monoubiquitination Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Centriole Replication Negative Regulation Of Calcium Ion Import Intraciliary Transport Involved In Cilium Morphogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Positive Regulation Of NK T Cell Differentiation Interferon-gamma Secretion Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromosome Organization Regulation Of Centriole Replication Histone H2A Monoubiquitination Aggresome Assembly Regulation Of Cellular Process Response To Peptidoglycan Microtubule Severing Transcription, DNA-templated Histone H4-R3 Methylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cytoskeleton Organization RNA Biosynthetic Process Negative Regulation Of Viral Release From Host Cell Histone H2A Ubiquitination Negative Regulation Of Centrosome Duplication Peptidyl-arginine N-methylation Lymph Node Development Peyer's Patch Development Regulation Of Transcription, DNA-templated Regulation Of Tumor Necrosis Factor Biosynthetic Process Response To Muramyl Dipeptide Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Difference) ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Intersection) ?