IKZF1 and C19orf66

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF1	C19orf66
Gene Name		IKAROS family zinc finger 1 (Ikaros)	chromosome 19 open reading frame 66
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Pericentric Heterochromatin Cytoplasm Protein Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation Transcription, DNA-templated Cell Cycle Mesoderm Development Chromatin Modification B Cell Differentiation T Cell Differentiation Forebrain Development Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Thymus Development Peyer's Patch Development Positive Regulation Of NK T Cell Differentiation Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23512250 19684603 19684604) Crohn's disease ( 21102463) Hippocampal atrophy ( 19668339) IgG glycosylation ( 23382691) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 19838193)
Protein-Protein Interactions		75 interactors: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C19orf66 C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 CTBP2 DCX DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FRMD6 GLRX3 GMCL1P1 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MTA1 NEK6 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I WTAP ZMAT2 ZNF417 ZNF581	32 interactors: ADAMTSL4 CADPS CCDC136 DRICH1 DTNBP1 IKZF1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 LZTS2 MAGEA1 MDFI MEOX2 MID2 MTUS2 NOTCH2NL PDE4DIP SPRY2 SSX2IP TCF4 TERF1 TNS2 TRAF1
Entrez ID		10320	55337
HPRD ID		04318	07747
Ensembl ID		ENSG00000185811	ENSG00000130813
Uniprot IDs		Q13422	Q9NUL5
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Organelle Organization Chromosome Organization Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA Repair Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Splicing	Regulation Of Signal Transduction Developmental Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Signaling Cellular Localization Organelle Localization Cellular Component Assembly Negative Regulation Of Biosynthetic Process Negative Regulation Of Wnt Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Vesicle Localization Protein Complex Assembly Positive Regulation Of Neutrophil Differentiation Negative Regulation Of Signal Transduction Cellular Macromolecular Complex Assembly Anatomical Structure Development Organelle Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Protein Kinase B Signaling Embryonic Organ Morphogenesis Negative Regulation Of Protein Localization To Nucleus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Establishment Of Organelle Localization Cellular Protein Complex Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Microtubule-based Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Telomeric Loop Formation Age-dependent Telomere Shortening Cell Cycle Establishment Of Localization In Cell Positive Regulation Of Intracellular Signal Transduction Telomere Maintenance Via Telomere Shortening Catecholamine Secretion Maintenance Of DNA Repeat Elements Negative Regulation Of Cellular Response To Growth Factor Stimulus Synaptic Vesicle Transport Multicellular Organism Growth Regulation Of Apoptotic Process Regulation Of Cellular Process Multicellular Organismal Development Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Protein Kinase B Signaling
Tagcloud ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Difference) ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Intersection) ?